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ThesisItem Open Access PREVALENCE OF YOKE GALL IN BULLOCKS- ITS MANAGEMENT(KVAFSU, Bidar, 2005-06-01) MANJUNATH PATIL; B.V. SHIVAPRAKASHSTUDY ON PREVALENCE OF YOKE GALL, ITS MEDICAL AND SURGICAL TREATMENT IN BULLOCKS Manjunath Patil August-2005 Dr. B. V. Shivaprakash Major Advisor ABSTRACT Prevalence of yoke gall was studied under three different situations i.e., among clinical cases, among animals disposed for sale and slaughter. Classification and evaluation of eight different treatments was made in 57 clinical cases of yoke gall. Prevalence of yoke gall was studied in nine different locations of Karnataka State among clinical cases presented for five retrospective years from 2000 to 2004. Out of 2,61,882 total cases, 70,896 were suffering from different surgical disorders. Out of these, 2,081 cases had yoke gall with an overall prevalence of 0.79%; and prevalence among surgical cases was 2.94%. Out of 2,225 cattle and buffaloes disposed for sale, 38 bullocks were affected with yoke gall showing the prevalence of 1.71%. Out of 1,148 animals disposed for slaughter at Bangalore slaughter house and Chitaguppa slaughter house, 33 bullocks were found affected with yoke gall showing the prevalence of 2.98%. The prevalence of acute yoke gall was maximum (40.13%) in clinical situation; subacute yoke gall was maximum (52.63%) among the animals disposed for sale; and the chronic was maximum (53.06%) among the animals disposed for slaughter. The prevalence was maximum in rainy season (46.23%) followed by winter (31.43%). The prevalence was maximum in the bullocks of 6 to 8 years of age (48.42%). The prevalence was maximum in males (88.42%). Based on clinical and hisptopathological features a standard list of classification was given to yoke gall. Haematobiochemical and histological features of each type were documented. Fifty seven bullocks were divided into eight groups for the evaluation of treatment. In group I, diclofenac sodium injection and topical application of Khand ointment (turmeric and lime juice) were given. There was no reduction in swelling of acute and subacute yoke gall during the first 15 days and only 25% reduction was seen after 30 days. In group II, diclofenac sodium injection and topical application of Khand ointment and dimethyl sulfoxide liquid were used. Initially no response and after one month only 25% reduction was seen in these bullocks. In group III, only topical application of dimethyl sulfoxide was employed. Response was negligible during initial 15 days and slight reduction (25%) was seen after 30 days in bullocks with acute and subacute yoke gall. In group IV, intravenous dimethyl sulfoxie @ 1.0 g/kg b.wt. resulted in 50% of reduction of acute yoke gall on third day, 75% reduction on seventh day, 90% reduction on 15 th day and complete reduction on 30 th day. In group V, dexamethasone injection was given directly into the swelling. The acute yoke gall showed 50% reduction in swelling on third day, 75% on seventh day and almost complete reduction on 30 th day. In group VI, herbal treatment using paste of root of Triumfetta rotundifolia and leaves of Dregia volubilis were applied. The acute yoke galls showed 25% reduction on third day, 50% reduction on seventh day and complete absorption of fluid by 30 th day. The response was partial for subacute yoke gall and nil for chronic fibrosed yoke gall in groups IV, V & VI. In group VII, surgical drainage of acute yoke galls by stab incision resulted in immediate reduction but required second incision due to reaccumulation. In group VIII, surgical excision was followed in nine bullocks with chronic yoke galls which resulted in 100% improvement. There was no change in haematological values before and after treatment. There was slight increase in SGPT level and marked increase in LDH levels before and 30 days after treatment in all the groups.ThesisItem Open Access STUDIES ON THE EFFECTS OF DEXMEDITOMIDINE PREMEDICATION ON KETAMINE INDUCTION AND ISOFLURANE GENERAL ANAESTHESIA IN CATTLE(KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2017-12-01) MUNIRAJU, H.M.; L. RANGANATHThe study was conducted in cattle to standardizethedosage of dexmedetomidine as premedicant in cattle and to study the influence of dexmeditomidine premedication on ketamine induction and isoflurane general anaesthesia. During the present study the following parameters were assessed: (i) physiological parameters like rectal temperature, heart rate and respiratory rate,(ii) hematological parameters viz., total erythrocyte count (TEC), hemoglobin concentration (Hb), packed cell volume (PCV), total leukocyte count (TLC), differential leukocyte count (DLC),(iii)biochemical parameters like aspartate aminotransferase (AST), blood urea nitrogen(BUN), blood glucose and creatinine, (iv) blood gas parameters like PaO2, PaCO2 and blood pH (v) heamodynamic parameters like electrocardiography (ECG) and blood pressure (BP) (vi) anaesthetic parameters such as thequality of sedation, induction time, duration of anaesthesia, recovery time, extubation time, time for sternal recumbency and time for unassisted standing were assessed during the period of anaesthesia. Results revealed, in all the animals there were non-significant minor alterations in physiological, hematological and biochemical parameters, whereas some significant changes were observed in PaO2 and changes were only transient and within normal physiological limits. In the present study dexmedetomidine caused the smooth, effective, satisfactory and adequate sedation in three minutes of its administration and facilitated the induction of anaesthesia with minimal changes physiological parameters of cattle subjected for general anaesthesia. Findings were suggestive of anaesthetic protocol employed in the study was safe and effective provided the rapid and smooth induction along with faster recovery in all the animals during the study without any untowardevents or the complications.ThesisItem Open Access ROMIFIDINE AND XYLAZINE SEDATION WITH KETAMINE-ISOFLURANE ANAESTHESIA FOR SURGERIES IN BUFFALOES(KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2019-08) SAGAR PANDAV; (S. M. USTURGE)The present study was carried out in 12 clinical cases of buffaloes of either sex presented for various surgical procedures at Veterinary College, Bidar. The sedative effects of romifidine and xylazine for ketamine-isoflurane general anaesthesia in buffaloes were compared. The buffaloes were randomly divided into two groups consisting of six buffaloes in each group. The buffaloes of group I were administered with romifidine hcl @ 10 μg/kg body weight IV followed by ketamine hydrochloride @ (3 mg/kg, I/V) and maintained with isoflurane @ (1-2 %). The buffaloes of group II were administered with xylazine @ 0.1 mg/kg body weight IV followed by ketamine hydrochloride @ (3 mg/kg, I/V) and maintained with isoflurane @ (1-2%). The anaesthetic combinations were evaluated based on clinical, physiological, haemodynamic and haematobiochemical observations. Onset of sedation and down time to sternal recumbency was faster in the buffaloes premedicated with romifidine. Better analgesia, degree of sedation, muscle relaxation and faster induction and recovery was noticed in romifidine group-I as compared to xylazine group-II for ketamine-isoflurane general anaesthesia in buffaloes. Respiratory depression, bradycardia and decrease in mean arterial pressure were more severe in buffaloes premedicated with romifidine when compared to buffaloes premedicated with xylazine during ketamine-isoflurane anaesthesia. Haematobiochemical parameters though changed non-significantly during general anaesthesia in both the groups, it was only transient and not alaraming to suggest any pathological condition. Hence romifidine as a premedicant can be preferred over xylazine ketamine-isoflurane induced general anaesthesia buffaloesThesisItem Open Access STUDIES ON EFFICACY OF ZAP STRAP METHOD OF TREATMENT FOR MALIGNANT TUMOURS OF SKIN AND SUBCUTANEOUS TISSUE IN DOGS(KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2019-09) SUNIL C L; Dr. B. N. NAGARAJAStudy on application of zap strap method of treatment around the tumour mass was carried out in 6 dogs presented to the Veterinary College Hospital, Bangalore. Selection of the patients was based on Histopathological confirmation of malignant tumour of skin and subcutaneous tissue. With local infiltration of lignocaine 2%, zap strap was applied in all the cases around tumour mass. Gross changes like blackish discoloration of tumour mass were noticed before slough off. In all cases tumour mass sloughed off by mean of 4ThesisItem Open Access STUDIES ON APPLICATION OF NEGATIVE PRESSURE WOUND THERAPY FOR NAVAL ILL / JOINT ILL IN CALVES(KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2018-07) GAVKAR MANDAR YESHWANT; Dr. B. N. NAGARAJAThe studies on application of Negative Pressure Wound Therapy for joint ill in calves was carried out in calves found to be suffering from joint ill presented to the Department of Veterinary Surgery and Radiology, Veterinary College Hebbal, Bangalore. Six clinical cases of calves were subjected to the NPWT to check the outcome. The gross changes, clinical signs, haematological and biochemical parameters and the radiographic findings were recorded before the treatment and on 7th, 14th, 21st and 28th day after the treatment. A significant variation in the rectal temperature was noticed in all the cases. Among the biochemical pThesisItem Open Access STUDIES ON THE EFFECT OF ROMIFIDINE PREMEDICATION ON KETAMINE INDUCTION AND ISOFLURANE MAINTENANCE GENERAL ANAESTHESIA IN CATTLE(KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2018-10) ANILKUMAR. B.N.; L. RANGANATHThe study was conducted in cattle to standardize the Romifidine-Ketamine- Isoflurane anaesthetic protocol. During the present study the following parameters were assessed: A. Physiological parameters like rectal temperature, heart rate, pulse rate, respiratory rate, Electrocardiogram, Mean arterial pressure. B. Hematological parameters viz., total erythrocyte count (TEC), hemoglobin concentration (Hb), packed cell volume (PCV), total leukocyte count (TLC), differential leukocyte count (DLC), C. Biochemical parameter like aspartate aminotransferase (AST), blood urea nitrogen, serum creatinine and blood glucose. D. Blood gas like PaO2, PaCO2 and blood pH analyses were also done. The quality of sedation, induction and anaesthesia were assessed based on the signs shown by the animals during the period of anaesthesia. The anaesthetic parameters such as the onset of sedation, induction time, attaining surgical plane of anaesthesia, duration of anaesthesia, recovery time, extubation time, time for sternal recumbency and time for unassisted standing were assessed during the period of anaesthesia. Results revealed, in all the animals there were non-significant minor alterations in physiological, hematological and biochemical parameters, whereas some significant changes were observed in PaO2, PaCO2 and were returned to normalcy during recovery period. The induction and recovery of anaesthesia were faster and rapid respectively in the present study. Findings were suggestive of Romifidine-Ketamine-Isoflurane anaesthetic protocol employed in the study was safe and effective. In conclusion, the general anaesthesia in cattle may be carried out safely and effectively by using the anaesthetic protocol employed in the present study.ThesisItem Open Access COMPARATIVE STUDIES ON INFLUENCE OF RIGHT AND LEFT LATERAL RECUMBENCY ON VERTEBRAL HEART SCORE IN PUG BREED OF DOGS(KARNATAKA VETERINARY, ANIMAL AND FOISHERIE'S SCIENCES UNIVERSITY, BIDAR, 2019-10) RAMYA, M. N.; Prof. (Dr.) NAGARAJA, B. N.A study on influence of right and left lateral recumbency on Vertebral Heart Score (VHS) in Pug breed of dogs (12) presented to Veterinary College Hospital, Hassan was carried out in a period of one year. In this study, the overall occurrence of cardiac diseases was 1.28% in dogs, irrespective of breeds. The occurrence of cardiac disease in Pug breed of dogs was 16.98%, highest in age group of 2-6 years (68.68%) and in female dogs (66.66%). The VHS in healthy Pug breed of dogs (Group A) was 10.28 + 0.20v and 10.08 + 0.19v in right and left lateral recumbency, respectively. VHS in Pug breed of dogs with cardiac diseases (Group B) was 11.63 + 0.24v and 11.41 + 0.21v in right and left lateral recumbency, respectively which was significantly greater than VHS of Group A. The VHS was subjectively correlated with the findings of thoracic radiography, electrocardiography and echocardiography. The right lateral VHS was significantly greater than left lateral VHS in both the groups. There was statistically non-significant variation in physiological parameter (temperature, except heart rate and respiratory rate), clinical parameter (BCS), haematological parameters (TEC, Hb, PCV, TLC and DLC) and biochemical parameters (serum creatinine, ALT and BUN) within and between the groups. VHS is the easily applicable, interpretable, non-invasive and accurate method for diagnosing cardiac disorders in dogs using thoracic radiographs. The VHS provided radiographic cardiac silhouette incorporating all chambers. The electrocardiography provided the electrical activities of the heart and echocardiography provided myocardial function and intracardiac morphology. Therefore, the combination of all these techniques will aid in assessing the severity and significance of known heart disease and helps to evaluate the therapeutic efficiency. Key words: Vertebral Heart Score (VHS), Pug, recumbency, dilated cardiomyopathy.ThesisItem Open Access COMPARATIVE STUDIES ON DIFFERENTTYPES OF INTRAOCULAR LENS IMPLANTATION FOLLOWING PHACOEMULSIFICATION IN CATARACTOUS DOGS(KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2018-06) SURESH, L.; Dr. L. RANGANATHThe present study was carried out among the dogs presented to Veterinary College Hospital, KVAFSU, Hebbal, Bangalore over a period of one year. A total of 13,200 cases were presented of which the number of dogs with cataract were 28 (0.21%), with highest percentage in Cocker Spaniel (25.00 %), followed by six in Pomeranian (21.43 %), four in Golden Retriever (14.29 %), three cases each in Labrador Retrievers, German Spitz and Non-descript (10.72 %) and two in German Shepherds (7.15%). Highest occurrence seen in the dogs aged 9-11 years range and high in male (53.60%) dogs. Pre and post-surgical evaluation of physiological, haematobiochemical parameters, visual function tests and clinical examination of eye were done. Accordingly, eighteen dogs were randomly selected and divided into three groups, Group A, B and C and were subjected for phacoemulsification followed with implantation of Rigid PMMA, Foldable hydrophilic acrylic and Foldable hydrophobic acrylic intra ocular lens respectively. The present study showed that there were no significant changes in physiological, hematological and biochemical parameters before and after the surgery. The techniques followed for the three groups were found to be adequate for restoring the vision. Comparatively, there was a lesser post-operative complications, better vision improvement and a higher owners response in Group C followed with B and A. In conclusion, the phacoemulsification followed with hydrophobic IOL implantation in Group C was proved to be superior in restoring vision with minimal post-operative complicationsThesisItem Open Access TRAMADOL PRE-EMPTIVE ANALGESIA FOR ROMIFIDINE-PROPOFOL AND XYLAZINE PROPOFOL INDUCTION WITH ISOFLURANE MAINTENANCE FOR SURGERIES OF DOGS(KARNATAKA VETERINARY ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2019-08) TOKAPPA, K. G; D. DILIP KUMARThe study was conducted to evaluate romifidine and xylazine as pre-anaesthetic for propofol-isoflurane anaesthesia in dogs for various surgeries. The study was conducted in 12 linical cases presented to VCC, Bidar. Twelve animals were randomly divided into two groups viz., Group-I and Group-II and consisting of six animals in each group. All the animals of boththe groups were atropinised at the rate of 0.045mg/kg and tramadol at the dose rate of 2 mg/kg body weight intramuscularly. Group-I animals received romifidine (10µg/kg) intravenously, In the Group-II animals xylazine (1mg/kg) was administered intravenously, anaesthesia was induced by administering propofol (3mg/kg) intravenously after 10 minutes of pre-anaesthetic administration in both the groups. Maintenance of anaesthesia was done under isoflurane in both groups. Anaesthetic combinations were compared by clinicophysiological, haemodynamic and haematobiochemical observations. Group I dogs showed quicker onset of sedation, narrowly quicker induction time and slower recovery than group II dogs. Degree of analgesia and muscle relaxation were greater in group I than group II dogs. Physiological parameters like rectal temperature and heart rate showed no significant variation in both groups. Respiratory rate decreased significantly in both the groups which was transitory in nature hence three combinations were well tolerated by the dogs. Haemodynamic observations did not vary significantly in both the groups. Haematological observations revealed that slight changes were observed in both the groups of dogs. Biochemical parameters did not vary significantly in both the groups, indicating that two anaesthetic combinations did not produce any adverse effects on liver and kidney function. Hence, Romifidine is an alternative pre-anaesthetic for xylazine for propofol - isoflurane anaesthesia for various surgeries in dogs. However, good analgesia and excellent muscle relaxation were observed in Romifidine-propofol-isoflurane anaesthesia in dogs