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Theses (PG)

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2017 - 201915
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Subject: Veterinary Surgery and Radiology × End date: 2019 × Start date: 2017 × Thesis Type: M.V.Sc. ×
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Now showing 1 - 9 of 15
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    ThesisItemOpen Access
    STUDIES ON THE EFFECTS OF DEXMEDITOMIDINE PREMEDICATION ON KETAMINE INDUCTION AND ISOFLURANE GENERAL ANAESTHESIA IN CATTLE
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2017-12-01) MUNIRAJU, H.M.; L. RANGANATH
    The study was conducted in cattle to standardizethedosage of dexmedetomidine as premedicant in cattle and to study the influence of dexmeditomidine premedication on ketamine induction and isoflurane general anaesthesia. During the present study the following parameters were assessed: (i) physiological parameters like rectal temperature, heart rate and respiratory rate,(ii) hematological parameters viz., total erythrocyte count (TEC), hemoglobin concentration (Hb), packed cell volume (PCV), total leukocyte count (TLC), differential leukocyte count (DLC),(iii)biochemical parameters like aspartate aminotransferase (AST), blood urea nitrogen(BUN), blood glucose and creatinine, (iv) blood gas parameters like PaO2, PaCO2 and blood pH (v) heamodynamic parameters like electrocardiography (ECG) and blood pressure (BP) (vi) anaesthetic parameters such as thequality of sedation, induction time, duration of anaesthesia, recovery time, extubation time, time for sternal recumbency and time for unassisted standing were assessed during the period of anaesthesia. Results revealed, in all the animals there were non-significant minor alterations in physiological, hematological and biochemical parameters, whereas some significant changes were observed in PaO2 and changes were only transient and within normal physiological limits. In the present study dexmedetomidine caused the smooth, effective, satisfactory and adequate sedation in three minutes of its administration and facilitated the induction of anaesthesia with minimal changes physiological parameters of cattle subjected for general anaesthesia. Findings were suggestive of anaesthetic protocol employed in the study was safe and effective provided the rapid and smooth induction along with faster recovery in all the animals during the study without any untowardevents or the complications.
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    ThesisItemOpen Access
    ROMIFIDINE AND XYLAZINE SEDATION WITH KETAMINE-ISOFLURANE ANAESTHESIA FOR SURGERIES IN BUFFALOES
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2019-08) SAGAR PANDAV; (S. M. USTURGE)
    The present study was carried out in 12 clinical cases of buffaloes of either sex presented for various surgical procedures at Veterinary College, Bidar. The sedative effects of romifidine and xylazine for ketamine-isoflurane general anaesthesia in buffaloes were compared. The buffaloes were randomly divided into two groups consisting of six buffaloes in each group. The buffaloes of group I were administered with romifidine hcl @ 10 μg/kg body weight IV followed by ketamine hydrochloride @ (3 mg/kg, I/V) and maintained with isoflurane @ (1-2 %). The buffaloes of group II were administered with xylazine @ 0.1 mg/kg body weight IV followed by ketamine hydrochloride @ (3 mg/kg, I/V) and maintained with isoflurane @ (1-2%). The anaesthetic combinations were evaluated based on clinical, physiological, haemodynamic and haematobiochemical observations. Onset of sedation and down time to sternal recumbency was faster in the buffaloes premedicated with romifidine. Better analgesia, degree of sedation, muscle relaxation and faster induction and recovery was noticed in romifidine group-I as compared to xylazine group-II for ketamine-isoflurane general anaesthesia in buffaloes. Respiratory depression, bradycardia and decrease in mean arterial pressure were more severe in buffaloes premedicated with romifidine when compared to buffaloes premedicated with xylazine during ketamine-isoflurane anaesthesia. Haematobiochemical parameters though changed non-significantly during general anaesthesia in both the groups, it was only transient and not alaraming to suggest any pathological condition. Hence romifidine as a premedicant can be preferred over xylazine ketamine-isoflurane induced general anaesthesia buffaloes
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    ThesisItemOpen Access
    STUDIES ON EFFICACY OF ZAP STRAP METHOD OF TREATMENT FOR MALIGNANT TUMOURS OF SKIN AND SUBCUTANEOUS TISSUE IN DOGS
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2019-09) SUNIL C L; Dr. B. N. NAGARAJA
    Study on application of zap strap method of treatment around the tumour mass was carried out in 6 dogs presented to the Veterinary College Hospital, Bangalore. Selection of the patients was based on Histopathological confirmation of malignant tumour of skin and subcutaneous tissue. With local infiltration of lignocaine 2%, zap strap was applied in all the cases around tumour mass. Gross changes like blackish discoloration of tumour mass were noticed before slough off. In all cases tumour mass sloughed off by mean of 4
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    ThesisItemOpen Access
    STUDIES ON APPLICATION OF NEGATIVE PRESSURE WOUND THERAPY FOR NAVAL ILL / JOINT ILL IN CALVES
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2018-07) GAVKAR MANDAR YESHWANT; Dr. B. N. NAGARAJA
    The studies on application of Negative Pressure Wound Therapy for joint ill in calves was carried out in calves found to be suffering from joint ill presented to the Department of Veterinary Surgery and Radiology, Veterinary College Hebbal, Bangalore. Six clinical cases of calves were subjected to the NPWT to check the outcome. The gross changes, clinical signs, haematological and biochemical parameters and the radiographic findings were recorded before the treatment and on 7th, 14th, 21st and 28th day after the treatment. A significant variation in the rectal temperature was noticed in all the cases. Among the biochemical p
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    ThesisItemOpen Access
    STUDIES ON THE EFFECT OF ROMIFIDINE PREMEDICATION ON KETAMINE INDUCTION AND ISOFLURANE MAINTENANCE GENERAL ANAESTHESIA IN CATTLE
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2018-10) ANILKUMAR. B.N.; L. RANGANATH
    The study was conducted in cattle to standardize the Romifidine-Ketamine- Isoflurane anaesthetic protocol. During the present study the following parameters were assessed: A. Physiological parameters like rectal temperature, heart rate, pulse rate, respiratory rate, Electrocardiogram, Mean arterial pressure. B. Hematological parameters viz., total erythrocyte count (TEC), hemoglobin concentration (Hb), packed cell volume (PCV), total leukocyte count (TLC), differential leukocyte count (DLC), C. Biochemical parameter like aspartate aminotransferase (AST), blood urea nitrogen, serum creatinine and blood glucose. D. Blood gas like PaO2, PaCO2 and blood pH analyses were also done. The quality of sedation, induction and anaesthesia were assessed based on the signs shown by the animals during the period of anaesthesia. The anaesthetic parameters such as the onset of sedation, induction time, attaining surgical plane of anaesthesia, duration of anaesthesia, recovery time, extubation time, time for sternal recumbency and time for unassisted standing were assessed during the period of anaesthesia. Results revealed, in all the animals there were non-significant minor alterations in physiological, hematological and biochemical parameters, whereas some significant changes were observed in PaO2, PaCO2 and were returned to normalcy during recovery period. The induction and recovery of anaesthesia were faster and rapid respectively in the present study. Findings were suggestive of Romifidine-Ketamine-Isoflurane anaesthetic protocol employed in the study was safe and effective. In conclusion, the general anaesthesia in cattle may be carried out safely and effectively by using the anaesthetic protocol employed in the present study.
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    ThesisItemOpen Access
    COMPARATIVE STUDIES ON INFLUENCE OF RIGHT AND LEFT LATERAL RECUMBENCY ON VERTEBRAL HEART SCORE IN PUG BREED OF DOGS
    (KARNATAKA VETERINARY, ANIMAL AND FOISHERIE'S SCIENCES UNIVERSITY, BIDAR, 2019-10) RAMYA, M. N.; Prof. (Dr.) NAGARAJA, B. N.
    A study on influence of right and left lateral recumbency on Vertebral Heart Score (VHS) in Pug breed of dogs (12) presented to Veterinary College Hospital, Hassan was carried out in a period of one year. In this study, the overall occurrence of cardiac diseases was 1.28% in dogs, irrespective of breeds. The occurrence of cardiac disease in Pug breed of dogs was 16.98%, highest in age group of 2-6 years (68.68%) and in female dogs (66.66%). The VHS in healthy Pug breed of dogs (Group A) was 10.28 + 0.20v and 10.08 + 0.19v in right and left lateral recumbency, respectively. VHS in Pug breed of dogs with cardiac diseases (Group B) was 11.63 + 0.24v and 11.41 + 0.21v in right and left lateral recumbency, respectively which was significantly greater than VHS of Group A. The VHS was subjectively correlated with the findings of thoracic radiography, electrocardiography and echocardiography. The right lateral VHS was significantly greater than left lateral VHS in both the groups. There was statistically non-significant variation in physiological parameter (temperature, except heart rate and respiratory rate), clinical parameter (BCS), haematological parameters (TEC, Hb, PCV, TLC and DLC) and biochemical parameters (serum creatinine, ALT and BUN) within and between the groups. VHS is the easily applicable, interpretable, non-invasive and accurate method for diagnosing cardiac disorders in dogs using thoracic radiographs. The VHS provided radiographic cardiac silhouette incorporating all chambers. The electrocardiography provided the electrical activities of the heart and echocardiography provided myocardial function and intracardiac morphology. Therefore, the combination of all these techniques will aid in assessing the severity and significance of known heart disease and helps to evaluate the therapeutic efficiency. Key words: Vertebral Heart Score (VHS), Pug, recumbency, dilated cardiomyopathy.
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    ThesisItemOpen Access
    TRAMADOL PRE-EMPTIVE ANALGESIA FOR ROMIFIDINE-PROPOFOL AND XYLAZINE PROPOFOL INDUCTION WITH ISOFLURANE MAINTENANCE FOR SURGERIES OF DOGS
    (KARNATAKA VETERINARY ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2019-08) TOKAPPA, K. G; D. DILIP KUMAR
    The study was conducted to evaluate romifidine and xylazine as pre-anaesthetic for propofol-isoflurane anaesthesia in dogs for various surgeries. The study was conducted in 12 linical cases presented to VCC, Bidar. Twelve animals were randomly divided into two groups viz., Group-I and Group-II and consisting of six animals in each group. All the animals of boththe groups were atropinised at the rate of 0.045mg/kg and tramadol at the dose rate of 2 mg/kg body weight intramuscularly. Group-I animals received romifidine (10µg/kg) intravenously, In the Group-II animals xylazine (1mg/kg) was administered intravenously, anaesthesia was induced by administering propofol (3mg/kg) intravenously after 10 minutes of pre-anaesthetic administration in both the groups. Maintenance of anaesthesia was done under isoflurane in both groups. Anaesthetic combinations were compared by clinicophysiological, haemodynamic and haematobiochemical observations. Group I dogs showed quicker onset of sedation, narrowly quicker induction time and slower recovery than group II dogs. Degree of analgesia and muscle relaxation were greater in group I than group II dogs. Physiological parameters like rectal temperature and heart rate showed no significant variation in both groups. Respiratory rate decreased significantly in both the groups which was transitory in nature hence three combinations were well tolerated by the dogs. Haemodynamic observations did not vary significantly in both the groups. Haematological observations revealed that slight changes were observed in both the groups of dogs. Biochemical parameters did not vary significantly in both the groups, indicating that two anaesthetic combinations did not produce any adverse effects on liver and kidney function. Hence, Romifidine is an alternative pre-anaesthetic for xylazine for propofol - isoflurane anaesthesia for various surgeries in dogs. However, good analgesia and excellent muscle relaxation were observed in Romifidine-propofol-isoflurane anaesthesia in dogs
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    ThesisItemOpen Access
    COMPARATIVE EVALUATION OF XYLAZINE – KETAMINE AND DEXMEDETOMIDINE - KETAMINE BOLUS INDUCTION COMBINATION UNDER ISOFLURANE ANAESTHESIA IN CANINES UNDERGOING VARIOUS SURGERIES
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2019-08) SWAROOP, G. L; Dr. DILIPKUMAR, D
    The study was conducted to evaluate xylazine – ketamine and dexmedetomidine – ketamine bolus induction intravenously and maintenance by isoflurane anaesthesia in dogs for various surgeries. The study was conducted in 12 clinical cases presented to VCC, Bidar. Twelve animals were randomly divided into two groups viz., Group-I and group-II consisting of six animals in each group. All the animals in two groups were atropinised at the rate of 0.045mg/kg via., intramuscularly. Group-I animals received xylazine – ketamine bolus (1 mg/kg and 10 mg/kg respectively) intravenously, in the Group-II animals dexmedetomidine – ketamine (10 µg/kg and 10 mg/kg respectively) was administered intravenously, after dogs reaching surgical plane of anaesthesia endotracheal intubation was done for isoflurane (1-2 %) anaesthesia as a maintenance administration in all the animals of two groups. Anaesthetic combinations were compared by clinicophysiological, haemodynamic and hematobiochemical observations. Group II dogs showed quicker and smooth induction time and prolonged recovery than group I. Degree of analgesia and muscle relaxation were greater in group I than group II. Physiological parameters like rectal temperature showed no significant variation in two groups. Respiratory rate and heart rate had significant difference in two groups which was transitory in nature, hence two combinations were well tolerated by the dogs. Haemodynamic observations had varied significantly in two groups. Haematological observations revealed that slight changes were observed in two groups of dogs. Biochemical parameters were varied significantly in two groups. Hence, xylazine – ketamine bolus and dexmedetomidine – ketamine bolus combination provides cardiac, thoracic and abdominal relaxation, there by kept the animal in good surgical plane of anaesthesia. However, good analgesia and excellent muscle relaxation were observed in xylazine-ketamine bolus induction and isoflurane maintenance anaesthesia in dogs
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    ThesisItemOpen Access
    COMPARATIVE EVALUATION OF INDUCTION COMBINATIONS ROMIFIDINE-GUAIFENESIN KETAMINE AND DEXMEDETOMIDINE GUAIFENESIN-KETAMINE UNDER ISOFLURANE ANESTHESIA IN CATTLE
    (KARNATAKA VETERINARY ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2019-08) KUMAR SWAMY; (D. DILIP KUMAR
    The study was carried out to evaluate the feasibility of romifidine and dexmedetomidine sedation for guaifenesin, ketamine-isoflurane general anaesthesia for various surgeries in cattle. The study was carried out in 12 clinical cases of cattle presented to Veterinary Clinical Complex, Veterinary College Bidar for various surgical procedures. The cases were randomly divided into two groups consisting of six cattle in each group. The animals of group I were administered with romifidine (10 µg/kg, IV). The animals of group II were administered with dexmedetomidine hydrochloride (2.5µg/kg, IV) immediately followed by guaifenesin (50 mg/kg, 5% sol). After ten minutes, the anaesthesia was induced by administering ketamine hydrochloride (3 mg/kg, I/V) and maintained with isoflurane (1-2%) in both the groups. Though the induction and recovery were smooth and uneventful in both groups, faster onset of sedation, faster down time to sternal recumbency, early recovery time to regain sternal position and to assume standing position were noticed in cattle premedicated with romifidine than in cattle premedicated with dexmedetomidine for guaifenesin-ketamine-isoflurane general anaesthesia. Physiological and hemodynamic parameters like heart rate, respiratory rate, rectal temperature, mean arterial pressure and hemoglobin oxygen saturation were fluctuated within normal limit. Respiratory depression and bradycardia were more severe in cattle premedicated with romifidine when compared to cattle premedicated with dexmedetomidine. Haemoglobin, packed cell volume, total erythrocyte count and total leukocyte count decreased significantly at maximum depth of anaesthesia in both the groups. Neutrophilia and relative lymphocytopenia was recorded in both the groups. Biochemical parameters decreased significantly towards the end of anaesthetic period in both the groups, however, it was within normal physiological limits. In present study romifidine-guaifenesin-ketamine-isoflurane combination was ideal to perform major surgeries in cattle without any complications. However, dexmedetomidine hydrochloride as a premedication for guaifenesin-ketamine-isoflurane anaesthetic combination was less optimum at this given dose in cattle