COMPARATIVE EVALUATION OF INDUCTION AGENTS IN DRIP FORM USING GUAIFENESIN AND KETAMINE WITH OR WITHOUT DEXMEDETOMIDINE UNDER ISOFLURANE ANAESTHESIA FOR VARIOUS SURGERIES IN CATTLE
| dc.contributor.advisor | D. DILIP KUMAR | |
| dc.contributor.author | NEELKANTH | |
| dc.date.accessioned | 2023-02-09T11:22:15Z | |
| dc.date.available | 2023-02-09T11:22:15Z | |
| dc.date.issued | 2021-02 | |
| dc.description.abstract | The study was carried out to evaluate the feasibility of induction agents in drip form using guaifenesin and ketamine with or without dexmedetomidine under isoflurane anaesthesia for various surgeries in cattle. The present study was conducted in 12 clinical cases presented to Veterinary Clinical Complex, Veterinary College, Bidar for the treatment of various surgical affections in cattle. The cattle were randomly divided into two groups consisting of six animals in each group. The group- I animals were administered guaifenesin at the dose rate of 50 mg / kg body weight intravenously as 5% solution in normal saline along with ketamine at the dose rate of 3 mg/ kg body weight intravenously as drip form and maintained with isoflurane (1-2 %). The animals of group- II were administered with preanaesthetic dexmedetomidine hydrochloride (2.5 μg/kg, IV) after 5 minutes followed by guaifenesin at the dose rate of 50 mg / kg body weight intravenously as 5 % solution in normal saline along with ketamine at the dose rate of 3 mg/ kg body weight intravenously as drip form and maintained with isoflurane (1-2 %). Though the induction and recovery were smooth and uneventful in both groups, Induction time was significantly earlier in group-II animals. The recovery time, Recovery time to assume sternal recumbency, Recovery time to standing position was significantly quicker in group-I animals. The degree of analgesia and muscle relaxation was significantly greater in group-II animals induced with dexmedetomidine, guaifenesin and ketamine drip under isoflurane anaesthesia. Physiological parameters like heart rate shows significant difference between the groups. Respiratory rate and rectal temperature were decreased significantly at maximum depth of anaesthesia in both the groups. Respiratory depression and bradycardia were more severe in group-II (guaifenesin and ketamine drip with dexmedetomidine under isoflurane) animals compare to group-I animals. Hematobiochemical parameters like haemoglobin, packed cell volume, total erythrocyte count and total leukocyte count decreased significantly at maximum depth of anaesthesia in both the groups. Neutrophilia and relative lymphocytopenia was recorded in both the groups. Alanine transaminase, aspartate transaminase, serum creatinine, Serum urea nitrogen level increased significantly at maximum depth of anaesthesia in both the groups. However, biochemical values were decreased towards normal at 120 minute of post induction. In the present study both the anaesthetic protocols provided satisfactory surgical plane of anaesthesia in cattle. However, guaifenesin and ketamine drip with dexmedetomidine under isoflurane combination was ideal to perform major surgeries in cattle without any complications. | en_US |
| dc.identifier.uri | https://krishikosh.egranth.ac.in/handle/1/5810193541 | |
| dc.keywords | VETERINARY SURGERY AND RADIOLOGY | en_US |
| dc.language.iso | English | en_US |
| dc.pages | 188 | en_US |
| dc.publisher | KARNATAKA VETERINARY ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR | en_US |
| dc.sub | Veterinary Surgery and Radiology | en_US |
| dc.theme | VETERINARY SURGERY AND RADIOLOGY | en_US |
| dc.these.type | M.V.Sc. | en_US |
| dc.title | COMPARATIVE EVALUATION OF INDUCTION AGENTS IN DRIP FORM USING GUAIFENESIN AND KETAMINE WITH OR WITHOUT DEXMEDETOMIDINE UNDER ISOFLURANE ANAESTHESIA FOR VARIOUS SURGERIES IN CATTLE | en_US |
| dc.type | Thesis | en_US |