DIAGNOSIS AND THERAPEUTIC MANAGEMENT OF TRYPANOSOMIASIS IN DONKEYS

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dc.contributor.advisorN. A. PATIL
dc.contributor.authorMALLIKARJUN SANNADANI
dc.date.accessioned2023-12-21T12:17:30Z
dc.date.available2023-12-21T12:17:30Z
dc.date.issued2022
dc.description.abstractIn the present study was conducted on trypanosomiasis in donkeys of Bidar district, where 253 donkeys were screened for trypanosomiasis. A total of 17 donkeys were found to be positive for trypanosomiasis. The overall incidence of trypanosomiasis in the present study was 6.71 per cent (17/253) in donkeys. The agewise incidence was higher (18.60 %) in the 3-6 years age group. The month-wise incidence of trypanosomiasis in donkeys was higher in October (15.49 %). The sexwise incidence of trypanosomiasis of donkeys was more in males. Trypanosomiasis in donkeys showed clinical signs were unthriftiness, progressive weight loss, pale CMM, fever, swollen prescapular lymph nodes, corneal opacity and scrotal oedema. Clinical parameter Viz., RT, HR, RR and CLT were increased and paler CMM in trypanosomiasis of donkeys. The haemotological analysis revealed leukopenia neutropenia, lymphocytosis, anaemia, thrombocytopenia and biochemical analysis revealed hypoglycemia, hypoproteinemia, hypoalbuminemia, and significant (p <0.05) increase of A: G ratio, ALP, AST and ALT level in trypanosomiasis of donkeys. The diagnostic efficacy of various methods among these mHCT (82.35%) and PCR (100.00%) revealed high sensitivity and specificity. The gene sequencing and phylogenetic analysis revealed cattle like T. evansi infection in donkeys with nucleotide homology of cattle isolate (98.19 %) in India. The therapeutic efficacy of isometamidium and quinapyramine prosalt were both equally effective. Isometamidium chloride Hcl and quinapyramine sulphate and chloride both yielded successful therapeutic results in donkeys.
dc.identifier.urihttps://krishikosh.egranth.ac.in/handle/1/5810204080
dc.publisherKARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR-585226
dc.subVeterinary Medicine
dc.themeVeterinary Medicine
dc.these.typeM.V.Sc.
dc.titleDIAGNOSIS AND THERAPEUTIC MANAGEMENT OF TRYPANOSOMIASIS IN DONKEYS
dc.typeThesis
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