COMPARATIVE EVALUATION OF TILETAMINEZOLAZEPAM AND KETAMINE ANAESTHESIA IN ATROPINE, DEXMEDETOMIDINE AND BUTORPHANOL PREMEDICATED DOGS
Loading...
Date
2022-07
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
G. B. Pant University of Agriculture & Technology, Pantnagar-263145
Abstract
The present study involved 12 client-owned dogs that were brought to Dr. I.P.
Singh Veterinary Clinical Complex & Trauma Centre of College of Veterinary and Animal
Sciences, Pantnagar for surgical correction of various disease conditions. These 12 dogs
were randomly divided into group A and group B, with six animals in each group. All the
animals were pre-administered with atropine sulphate @ 0.03 mg/kg subcutaneously
followed 10 minutes later by intramuscular dexmedetomidine @ 7.5 ug/kg and 10 minutes
later, butorphanol was administered intramuscularly @ 0.2 mg/kg. Animals of group A
were induced by tiletamine-zolazepam while animals of group B were induced by ketamine
intravenously with a mean induction dose of 3.5± 0.18 mg/kg and 4.2± 0.1 mg/kg
respectively and the effects of these anaesthetic regimens on clinico-physiological,
haematological and biochemical parameters of animals were studied.
Induction was smooth and quick in both the groups A and B. However, group A
containing atropine-dexmedetomidine-butorphanol and tiletamine-zolazepam was found to
be a better choice than group B containing atropine-dexmedetomidine-butorphanol and
ketamine considering the facts that induction dose was significantly less, duration of
anesthesia was longer and muscle relaxation was excellent in group A. Supplementation
with maintenance doses was less required with the use of tiletamine-zolazepam as an
induction agent in group A. Animals of group B with ketamine as the induction agent
required a significantly higher amount of supplementation of anaesthetic agent at regular
intervals to complete the surgical procedures as compared to group A with tiletaminezolazepam
as the induction agent. Atropine, dexmedetomidine and butorphanol worked
well as preanesthetic agents and were found effective in facilitating smooth induction of
anaesthesia. Variations in the physiological, haematological and biochemical parameters
were transient and within the normal limits. The recovery in animals of both the groups A
and B of the present study was smooth and uneventful. Anaesthetic regimen of group A
using tiletamine-zolazepam as the induction agent can be safely and effectively used for
superficial and visceral soft tissue surgeries in dogs.
Description
Keywords
Citation
Thesis of MVSc.