COMPARATIVE EVALUATION OF TILETAMINEZOLAZEPAM AND KETAMINE ANAESTHESIA IN ATROPINE, DEXMEDETOMIDINE AND BUTORPHANOL PREMEDICATED DOGS
dc.contributor.advisor | Kandpal, Manjul | |
dc.contributor.author | Goswami, Arti | |
dc.date.accessioned | 2024-08-10T11:29:09Z | |
dc.date.available | 2024-08-10T11:29:09Z | |
dc.date.issued | 2022-07 | |
dc.description.abstract | The present study involved 12 client-owned dogs that were brought to Dr. I.P. Singh Veterinary Clinical Complex & Trauma Centre of College of Veterinary and Animal Sciences, Pantnagar for surgical correction of various disease conditions. These 12 dogs were randomly divided into group A and group B, with six animals in each group. All the animals were pre-administered with atropine sulphate @ 0.03 mg/kg subcutaneously followed 10 minutes later by intramuscular dexmedetomidine @ 7.5 ug/kg and 10 minutes later, butorphanol was administered intramuscularly @ 0.2 mg/kg. Animals of group A were induced by tiletamine-zolazepam while animals of group B were induced by ketamine intravenously with a mean induction dose of 3.5± 0.18 mg/kg and 4.2± 0.1 mg/kg respectively and the effects of these anaesthetic regimens on clinico-physiological, haematological and biochemical parameters of animals were studied. Induction was smooth and quick in both the groups A and B. However, group A containing atropine-dexmedetomidine-butorphanol and tiletamine-zolazepam was found to be a better choice than group B containing atropine-dexmedetomidine-butorphanol and ketamine considering the facts that induction dose was significantly less, duration of anesthesia was longer and muscle relaxation was excellent in group A. Supplementation with maintenance doses was less required with the use of tiletamine-zolazepam as an induction agent in group A. Animals of group B with ketamine as the induction agent required a significantly higher amount of supplementation of anaesthetic agent at regular intervals to complete the surgical procedures as compared to group A with tiletaminezolazepam as the induction agent. Atropine, dexmedetomidine and butorphanol worked well as preanesthetic agents and were found effective in facilitating smooth induction of anaesthesia. Variations in the physiological, haematological and biochemical parameters were transient and within the normal limits. The recovery in animals of both the groups A and B of the present study was smooth and uneventful. Anaesthetic regimen of group A using tiletamine-zolazepam as the induction agent can be safely and effectively used for superficial and visceral soft tissue surgeries in dogs. | |
dc.identifier.citation | Thesis of MVSc. | |
dc.identifier.uri | https://krishikosh.egranth.ac.in/handle/1/5810213119 | |
dc.language.iso | English | |
dc.pages | 55 p.p. | |
dc.publisher | G. B. Pant University of Agriculture & Technology, Pantnagar-263145 | |
dc.relation.ispartofseries | 10841 | |
dc.sub | Veterinary Surgery | |
dc.theme | Academic Research | |
dc.these.type | M.V.Sc. | |
dc.title | COMPARATIVE EVALUATION OF TILETAMINEZOLAZEPAM AND KETAMINE ANAESTHESIA IN ATROPINE, DEXMEDETOMIDINE AND BUTORPHANOL PREMEDICATED DOGS | |
dc.type | Thesis |