MOLECULAR DETECTION OF PARASITIC DISEASES IN CATTLE
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Date
2020-02
Authors
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Publisher
TANUVAS
Abstract
Microscopic detection and morphological identification of parasites from clinical specimens are
the gold standards for laboratory diagnosis of parasitic infections. The limitations of such diagnostic
assays include insufficient sensitivity and operator dependence. lmmunoassays for parasitic antigens
are not available for most parasitic infections and have not significantly improved the sensitivity of
laboratory detection. Advances in molecular detection by nucleic acid ampliļ¬cation may improve
the detection in asymptomatic infections with low parasitic burden. Rapidly accumulating genomic
data on parasites allow the design of polymerase chain reaction (PCR) primers directed towards
multi-copy gene targets, such as the ribosomal and mitochondrial genes, which further improve
the sensitivity and specificity (Wong et aI.2014).Protozoan parasites are responsible for causing
severe infections both in humans and animals worldwide and the infection is mainly transmitted by
arthropod vectors or through blood transfusion. The important hemoprotozoan diseases of veterinary
importance are trypanosomosis, theileriosis, babesiosis and anaplasmosis, which are caused by
several species of Trypanosoma, Theileria, Babesia and Anaplasma, respectively, in livestock (Singh
et al. 2007). The impact of these diseases on health and productivity of farm animals is huge
Description
TNV_TM_17-26-Feb-2020_215-219
Keywords
Veterinary Science, Veterinary Parasitology