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Book chapterItem Open Access Development and Sustainable Release Evaluation of Enrofloxacin Solid Lipid Nanopartilces(2014) Senthilkumar, P.; Arivuchelvan, A.; Jagadeeswaran, A.; Subramanian, N.; Senthilkumar, C.; Mekala, P.; TANUVASThe study was conducted to formulate the enrofloxacin solid lipid nanoparticles (SLNs) with sustained release profile and improved pharmacological activity. The enrofloxacin SLNs were prepared using tripalmitin as lipid carrier, tween 80 and span 80 as surfactants and poly vinyl alcohol (PVA) as a stabilizer by a hot homogenization coupled with ultrasonication method. The formulation were characterized for particle size, polydispersity index, zeta potential (using dynamic light scattering), shape (using atomic force microscopy), drug encapsulation efficiency (using by dialysis and ultracentrifugation methods), and in vitro drug release (using by dialysis).Book chapterItem Open Access Pharmacokinetics of Enrofloxacin Loaded Solid Lipid Nanoparticles following Oral Administration in Emu (Dromaius Novaehollandiae) Birds(2014) Senthilkumar, P.; Arivuchelvan, A.; Jagadeeswaran, A.; Subramanian, K.; Senthilkumar, C.; Mekala, P.; TANUVASThe study was conducted to formulate the enrofloxacin SLNs and evaluate its pharmacokinetic (PK) behaviour in emus. Enrofloxacin SLNs were prepared by a hot homogenization coupled with ultrasonication method and characterized for further investigation in emus. PK of native enrofloxacin was studied after i.v. and oral bolus administration at 10mg/kg in emus and it was compared with disposition kinetics of enrofloxacin SLNs. Enrofloxacin and its metabolite ciprofloxacin in plasma were estimated using HPLC and PKs were calculated by a noncompartmental analysis.Book chapterItem Open Access COLLECTION AND PRESERVATION OF HERBAL PLANTS(TANUVAS, Chennai, 2017) Ramakrishnan, V.; Sureshkumar, V.; Arivuchelvan, A.; Kanagarajadurai, K.; Satheshkumar, S.; TANUVASHerbal plants and plant-derived medicine are widely used in traditional cultures all over the world and they are becoming increasingly popular in modern society as natural alternatives to synthetic chemicals. Medicinal plant materials should be collected from the appropriate place, and during the appropriate season or time period to ensure the best possible quality of both source materials and finished products.Book chapterItem Open Access ETHNO-VETERINARY HERBAL PLANTS RESOURCES: WILD AND CULTIVATED PLANTS(2017) Sureshkumar, V.; Ramakrishnan, V.; Arivuchelvan, A.; Kanagarajadurai, K.; Satheshkumar, S.; TANUVASThe World Health Organization defines traditional medicine (herbal medicine) as "the sum total of the knowledge, skills, and practices based on the theories, beliefs, and experiences indigenous to different cultures, whether explicable or not, used in the maintenance of health as well as in the prevention, diagnosis, improvement or treatment of physical and mental illness" (WHO)