A STUDY ON THE ANTIOXIDANT ACTIONS OF FISH OIL & VIT. E + SELENIUM IN BROILERS
| dc.contributor.advisor | GOPALA REDDY, A(MAJOR) | |
| dc.contributor.advisor | KALAKUMAR, B. D. P. | |
| dc.contributor.advisor | ASHOK, V | |
| dc.contributor.advisor | RAJASEKHAR REDDY, A | |
| dc.contributor.author | SUSMITA ROUT | |
| dc.date.accessioned | 2018-10-01T06:57:07Z | |
| dc.date.available | 2018-10-01T06:57:07Z | |
| dc.date.issued | 2006 | |
| dc.description | THESES | en_US |
| dc.description.abstract | ABSTRACT: The antioxldant potentials of fish oil and vltamin E + selenlum was assessed for prophylactic and therapeutic management of free radical induced damage In an experimental model of oxidative stress induced by an ionophorous coccldiostat, maduramicin, at a toxic level of 8 ppm in feed A total of one hundred and twenty, male broiler chicks (Cobb strain) of day old age were randomly divided into eight groups, consisting of fifteen In each grol;p. Groups 1, 3 and 4 were maintained as basal diet control, f~sho il control and vlt E + Se control, respectively. Group 2 was maintarned with madurarnic~n @ 8 ppm in feed throughout for 6 wks and was maintained as toxic control wlthout any treatment. Groups 5 and 6 were fed w~thfi sh oil @ 2% in feed and vlt E (300 mglkg) + Se (0.3 mglkg). respecttvely along with madurarn~cln @ 8 pprn in feed throughout 6 wks of the experiment Groups 7 and 8 were fed wlth maduramlcin @ 8 pprn In feed for the first 4 wks (28 days) of study and thereafter, group 7 was given a fish oil supplemented feed @ 2% in feed and group 8 with vit E (300 mg/kg) + Se (0.3 mg/kg) In feed till the termination of the experiment at the end of 6Ih wk. Antioxidant defence profile (GSH-Px, GSH-R, catalase GSH, and TBARS), b~ornarkers of hepatic damage (AST), lipid profile (total cholesterol. triglycerides. HDL cholesterol and LDL cholesterol), prote~n profile (total protein, albumin, globulin and A/G ratio) and immune status (HI titre) were estimated at the end of 4" wk and 61h wk, except TBARS activity and HI titres 'that were estimated once, at the end of the 61h wk. Histopathological studies on liver, bursa, heart and skeletal muscle were conducted at the end of the 6'h wk. Antioxidant enzyme levels and biochemical parameters were significantly altered, and the histopathoiogical studies revealed separation of muscle fibre bundles In the myocardium and areas of necrosis in the liver in the maduramicin toxic control. These parameters were normal in the controls (groups 1.3 and 4), and other groups that were given fish oil and vit E + Se either prophylactically or therapeutically (groups 5, 6, 7 and 8). Thus, it is concluded that fish oil and vit E + Se were effective as ant~oxidants in preventing and countering oxidative stress by facilitating restoration of antioxidant defence mechanism. Hence, their supplementation would reduce the ~ncidence of economic losses due to stress. Beneficial effect of fish oil may be attributed to the presence of omega-3 fatty acids. | en_US |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810074557 | |
| dc.keywords | BROILERS;FISH OIL ;VIT. E;SELENIUM;ANTIOXIDANT | en_US |
| dc.language.iso | en | en_US |
| dc.pages | 129 | en_US |
| dc.publisher | SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA | en_US |
| dc.sub | Veterinary Pharmacology and Toxicology | en_US |
| dc.subject | null | en_US |
| dc.theme | A STUDY ON THE ANTIOXIDANT ACTIONS OF FISH OIL & VIT. E + SELENIUM IN BROILERS | en_US |
| dc.these.type | M.V.Sc. | en_US |
| dc.title | A STUDY ON THE ANTIOXIDANT ACTIONS OF FISH OIL & VIT. E + SELENIUM IN BROILERS | en_US |
| dc.type | Thesis | en_US |