IMMUNE RESPONSE TO PESTE DES PETITS RUMINANTS VIRUS VACCINE IN GOATS

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dc.contributor.authorGiridharan, P
dc.contributor.authorKaushik, S
dc.contributor.authorKrishnamohan Reddy, Y
dc.contributor.authorTANUVAS
dc.date.accessioned2021-08-05T07:22:18Z
dc.date.available2021-08-05T07:22:18Z
dc.date.issued2020
dc.descriptionTNV_IJSR_2020_25(2)181-185en_US
dc.description.abstractA study was undertaken to assess the immune response of the commercially available peste des petits ruminants virus (PPRV) vaccines in goats of Tamil Nadu under field conditions. Two commercial PPRV vaccines from manufacturers A and B, available in the state were used from 2016 to 2018. The serum samples were collected from the PPRV vaccinated goats on 0, 28, 90, 180 and 365 days post vaccination (DPV) for the four groups and tested for PPRV antibodies by competitive enzyme-linked immunosorbant assay (c-ELISA) and micro serum neutralisation test (mSNT). Group 1 (4 months to 1 yr of age) and Gr 4 (45 days-old) goats were vaccinated with either PPRV vaccine from vaccine manufacturer A or B; Gr 2 goats (>1 yr of age) which were previously vaccinated once with PPRV vaccine and revaccinated with PPRV vaccine from the same manufacturer A or B; Gr 3 goats (>1 yr of age) revaccinated with PPRV vaccine from manufacturer A, which were previously vaccinated once with PPRV vaccine from different manufacturer B and vice versa. In all the four groups, the mean percentage inhibition (PI) values on c-ELISA continued to increase from 0 DPV (21.28±0.54) to 90 DPV (83.88±0.70). Thereafter there was decline in the average PI values with the presence of PPRV antibody even at 365 DPV (83.88±0.70 to 54.19±0.78). The study suggested that vaccine from either of the manufacturer can be used for subsequent revaccination so as to produce rapid immune response.en_US
dc.identifier.urihttps://krishikosh.egranth.ac.in/handle/1/5810171468
dc.keywordsGoat, Immune response, Peste des petits ruminants, Vaccinationen_US
dc.language.isoEnglishen_US
dc.pages181-185en_US
dc.relation.ispartofseries;2
dc.subjectVeterinary Scienceen_US
dc.titleIMMUNE RESPONSE TO PESTE DES PETITS RUMINANTS VIRUS VACCINE IN GOATSen_US
dc.title.alternativeIndian Journal of Small Ruminantsen_US
dc.typeArticleen_US
dc.volume25en_US
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