Synthesis, characterization and antimicrobial activity of manganese, cobalt, iron and copper Schiff base metal complexes

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dc.contributor.advisor. Sachin Kumari)
dc.contributor.authorPanghal, Monika
dc.date.accessioned2022-01-05T09:34:45Z
dc.date.available2022-01-05T09:34:45Z
dc.date.issued2021-08
dc.description.abstractThe present study was undertaken for the synthesis, characterization and antimicrobial activity of manganese, cobalt, iron and copper Schiff base metal complexes conducted at Chaudhary Charan Singh Haryana Agricultural University, Hisar. Schiff base ligand, L1 (C19H14N4O3 ) was synthesized from the condensation reaction of p- benzoyl pyridine and p-nitrobenzohydrazide and their transition metal complexes of Mn(II), Fe(II), Co(II) and Cu(II) were prepared from the interaction of ligand with metal ions in methanolic medium in molar ratio 1:2 (M:L). The Schiff base ligand as well as its transition metal complexes are stable, coloured and non-hygroscopic in nature. The melting point of the ligand was found to be 126°C while complexes showed higher melting point in the range of 200-250°C which showed their higher stability. They are soluble in DMF, DMSO and CHCl3 . The value of molar conductivity of ligand and complexes lie in the range of 12-25 S m2 mol-1 which revealed their non electrolytic nature. The synthesized compounds were characterized by 1H-NMR, FTIR and UV-Vis spectral studies. The FTIR spectral study have shown the coordination of metal ion with Schiff base ligand through azomethine nitrogen at 1598 cm-1 . The electronic spectra showed the shift in wavelength to higher energy arising due to band that of n to π* transition which revealed the metal-ligand interaction. The ligand and the metal complexes were screened for their antimicrobial activity against five microbes; Bacillus, Pseudomonas, Rhizoctonia, Alternaria and Fusarium oxysporum. The ligand, L1 showed moderate antibacterial activity with inhibition zone in the range of 2.7-6 mm while the complexes showed higer antibacterial activity with inhibition zone in the range of 5-12 mm. Both the ligand as well as the complexes except that of copper complex were not effective in inhibiting the growth of fungal strains. The zone of inhibiton for copper complex was found in the range of 1.1-6.7 mm dpending upon the concentrationen_US
dc.identifier.urihttps://krishikosh.egranth.ac.in/handle/1/5810180387
dc.keywordsSchiff base ligand, Transition metal complexes, Antimicrobial activityen_US
dc.language.isoEnglishen_US
dc.pages49 + ven_US
dc.publisherCCSHAU, Hisaren_US
dc.subChemistryen_US
dc.themeSynthesis, characterization and antimicrobial activity of manganese, cobalt, iron and copper Schiff base metal complexesen_US
dc.these.typeM.Scen_US
dc.titleSynthesis, characterization and antimicrobial activity of manganese, cobalt, iron and copper Schiff base metal complexesen_US
dc.typeThesisen_US
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