Synthesis, characterization and antimicrobial activity of manganese, cobalt, iron and copper Schiff base metal complexes
Loading...
Date
2021-08
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
CCSHAU, Hisar
Abstract
The present study was undertaken for the synthesis, characterization and antimicrobial activity of
manganese, cobalt, iron and copper Schiff base metal complexes conducted at Chaudhary Charan Singh Haryana
Agricultural University, Hisar. Schiff base ligand, L1 (C19H14N4O3
) was synthesized from the condensation reaction
of p- benzoyl pyridine and p-nitrobenzohydrazide and their transition metal complexes of Mn(II), Fe(II), Co(II)
and Cu(II) were prepared from the interaction of ligand with metal ions in methanolic medium in molar ratio 1:2
(M:L). The Schiff base ligand as well as its transition metal complexes are stable, coloured and non-hygroscopic in
nature. The melting point of the ligand was found to be 126°C while complexes showed higher melting point in the
range of 200-250°C which showed their higher stability. They are soluble in DMF, DMSO and CHCl3
. The value
of molar conductivity of ligand and complexes lie in the range of 12-25 S m2 mol-1 which revealed their non electrolytic nature. The synthesized compounds were characterized by 1H-NMR, FTIR and UV-Vis spectral
studies. The FTIR spectral study have shown the coordination of metal ion with Schiff base ligand through
azomethine nitrogen at 1598 cm-1
. The electronic spectra showed the shift in wavelength to higher energy arising
due to band that of n to π* transition which revealed the metal-ligand interaction. The ligand and the metal
complexes were screened for their antimicrobial activity against five microbes; Bacillus, Pseudomonas,
Rhizoctonia, Alternaria and Fusarium oxysporum. The ligand, L1 showed moderate antibacterial activity with
inhibition zone in the range of 2.7-6 mm while the complexes showed higer antibacterial activity with inhibition
zone in the range of 5-12 mm. Both the ligand as well as the complexes except that of copper complex were not
effective in inhibiting the growth of fungal strains. The zone of inhibiton for copper complex was found in the
range of 1.1-6.7 mm dpending upon the concentration