STUDIES ON INDUCED DIABETES IN RATS WITH SPECIAL EMPHASIS ON COMBINED EFFICACY OF Gymnema sylvestre AND Eugenia jambolana
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Date
2020-02
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KARNATAKA VETERINARY ANIMAL FISHERIES SCIENCES UNIVERSITY.
Abstract
The present study was taken up to evaluate the combined antidiabetic effect of
Gymnema sylvestre and Eugenia jambolana along with glibenclamide in streptozotocin
induced diabetic rats for a period of 45 days. The various groups in this study included
normal control (Group I), diabetic control (Group II), diabetic rats treated with
glibenclamide (Group III), diabetic rats treated with a combination of Gymnema sylvestre
and Eugenia jambolana at half dose (Group IV), diabetic rats treated with a combination
of Gymnema sylvestre and Eugenia jambolana at full dose (Group V), diabetic rats
treated with a combination of Gymnema sylvestre and Eugenia jambolana along with
glibenclamide at half dose (Group VI) respectively. There was significant difference in
physiological, biochemical and pathomorphological parameters of diabetic rats when
compared to normal control rats. The alleviation of diabetic effects and its complications
induced