PREVALENCE, DIAGNOSIS AND THERAPEUTIC EFFICACY OF CEPHALOSPORINS AGAINST CLINICAL MASTITIS IN BUFFALOES

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Date
2018-07
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KARNATAKA VETERINARY ANIMAL AND FISHERIES SCIENCE'SUNIVERSITY, BIDAR-585226
Abstract
The study was undertaken to know the prevalence of clinical mastitis, clinical and haemato-biochemical changes in the clinical mastitis affected buffaloes, comparative evaluation of CMT and EC and to evaluate the efficacy of different cephalosporin preparation against clinical mastitis in buffaloes. The overall prevalence of clinical mastitis in buffaloes was 5.45 per cent in the present study. Age wise prevalence of mastitis was highest in 6-8 years age group buffaloes. Season wise prevalence revealed higher prevalence of mastitis during rainy season. Quarter wise prevalence showed higher prevalence of mastitis in hind quarters and single quarter involvement was higher than the multiple quarters. Clinical parameters viz, rectal temperature, heart rate, respiration rate showed significantly higher values in clinical mastitis affected than the healthy control buffaloes. Haematology revealed significantly higher values of TLC and no significant changes in Hb, TEC and PCV. Differential leucocyte count revealed higher granulocytes and lower lymphocyte count in clinical mastitis affected buffaloes. Among the diagnostic tests used CMT was found to have the highest accuracy (79.17 %) followed by EC (73.61 %). The predominant bacteria in affected milk samples were Staphalococcus spp. followed by Streptococcus spp. and E. coli. In antibiotic sensitivity assay, the sensitivity was highest with Gentamicin (77.78 %). Among Cephalosporin preparations, Cefquinome was found most efficacious in the treatment of clinical mastitis in buffaloes.
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