A COMPARATIVE STUDY OF EPIDURAL KETAMINE AND MIDAZOLAM AS AN ADJUVANT TO ROPIVACAINE FOR SURGICAL MANAGEMENT OF UREMIC GOATS
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Date
2022
Authors
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Publisher
Birsa Agricultural University, Ranchi
Abstract
Rectal temperature and respiration showed transient and nonsignificant
changes within normal physiological limits
• Heart rate, systolic pressure, dystolic pressure and mean arterial
pressure exhibited significant fall in group 1 compared to other
Summary and Conclusion…
groups. The value in other groups showed significant rise at different
intervals as compared to base value.
• Analgesia in perineum, flank inguinal, upper part of hind limb, pedal,
tail was marked and complete even upto 60 minutes of observation in
group 1 whereas in other groups complete analgesia was achieved
upto 30 minutes.
• Motor incoordination was noticed for longer period of time in group 1
followed by group 2, group 4 and group 3
• Time of standing was longer in group 2 followed by group 4, group 1
and group 3. Recumbency was quickest in group 4 followed by group
1, group2 and group 3.
• Heamtological (Hb, PCV, TEC, TLC, DLC) values did not show any
significant variation within and among the groups
• A significant increase in neutrophil and relative significant decrease
in lymphocytes value at different intervals as compared to base value
was the consistent features in all the groups.
• ALT, AST, ALP and CPK recorded at different intervals did not
show any significant variation, whereas blood glucose, BUN and
creatinine value exhibited significant elevation within normal
physiological limits.
• On the basis of above findings, Ropivacaine and its combination with
ketamine and midazolam were suitable to achieve analgesia for tube
cystostomy procedure with transient changes in clinical,
hematological and hematobiochemical parameters.
• Combining ketamine and midazolam did not enhance the
effectiveness of ropivacaine. Hence, ropivacaine alone may be
recommended as epidural agent to achieve excellent and longer
duration of analgesia over the other groups. Large studies in this
aspect have been warranted.
Description
A COMPARATIVE STUDY OF EPIDURAL KETAMINE AND
MIDAZOLAM AS AN ADJUVANT TO ROPIVACAINE FOR
SURGICAL MANAGEMENT OF UREMIC GOATS