STUDIES ON COMPARATIVE EFFICACY OF INTRAVAGINAL STEROIDAL AND NON-STEROIDAL DRUGS IN ESTRUS SYNCHRONIZATION IN EWES
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Date
2022
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KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR
Abstract
The present study was conducted with the objective of comparing the efficacy of steroidal (Avikesil-S®) and non-steroidal (Letrozole) drugs combined with PGF2α in estrus synchronization in ewes maintained at department of LFC, VCH, Bengaluru. Twenty four apparently healthy non pregnant ewes were randomly alloted into two groups with 12 each. Group I and Group II was treated with intravaginal Letrozole sponges and Avikesil-S® sponges for seven days, respectively. All the ewes were injected (i.m) with 125 μg of PGF2ɑ at the time of sponge removal. Trans rectal ultrasound scanning was done on day 0, 3 and 7th day post sponge insertion. The number and size of follicles on ovaries did not differ between both the groups on day 0 and 3 but difference in number between Group I (2.83 ± 0.40) and Group II (1.83 ± 0.17) was recorded on day 7. The ewes were kept under observation until pregnancy diagnosis on day 30 post mating using Ultrasound. Cent per cent sponge retention was documented among the study groups with 83.33 per cent estrus response. The interval to estrus in Group I (89.4 ± 2.24 h) was significantly higher (p< 0.05) than in Group II (45.59 ± 1.57 h). However, the conception rate (70.00 % vs 50.00 %) and duration of estrus (34.85 ± 1.83 h vs 34.7 ± 1.31 h) did not differ statistically (P>0.05) between the group I and II, but the conception rate in Group I is higher when compared to Group II.
Key words: Ewes, Estrus synchronization, Letrozole, Avikesil-S®, Reproductive parameters.