EVALUATION OF FRUCTOSAMINE AS A BIOMARKER IN DIAGNOSIS OF DIABETES MELLITUS IN CANINES
Loading...
![Thumbnail Image](assets/images/Item.jpg)
Date
2017-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR
Abstract
The present study was undertaken to determine the levels of fructosamine,
comparative analysis of fructosamine and glycated haemoglobin and also for estimation
of associated parameters in diabetic dogs. Also a group of healthy, chronically ill and
pregnant dogs consisting of six animals were included in the study to establish the normal
concentration of fructosamine in each group. The chronically ill group was further
divided into three and the dogs suffering from chronic renal, cardiac and hepatic related
illness were included with two animals in each group. In the present study the nondescript dog was found to be affected in greater number. Highest incidence of diabetes
was recorded in the age group of six to twelve years. Female dogs were found to be more
prone in the present study and more particularly intact female dogs. Hematological
profile of the diabetic dogs revealed mild leukocytosis. Total protein and albumin values
were within normal range and serum biochemistry revealed no significant difference in
diabetic dogs with that of healthy dogs. The fructosamine concentration was least
affected in chronically ill dogs. Fructosamine, glycated haemoglobin and blood glucose
levels were significantly elevated with the mean values of 638.3 µmol/L, 9.27 per cent
and 416.5 mg/dl, respectively in diabetic dogs and showed positive correlation which
endorse the acceptance that fructosamine is useful as one of the valuable biomarkers for
diagnosis and management of diabetes in dogs.