STUDY ON THE EFFECT OF DIFFERENT DOSES OF PROGESTERONE ON POSTPARTUM ANOESTRUS AND FERTILITY IN CROSSBRED CATTLE
Loading...
Date
2008
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Birsa Agricultural University, Kanke, Ranchi, Jharkhand
Abstract
An experiment was conducted on 30 non-lactating anoestrus
crossbred cows of age between 5 to 8 years. They were divided in to
5 groups containing 6 animals in each. Different doses of
progesterone were injected for different days, intramuscularly.
Before start of the experiment animals were dewormed with broadspectrum
anthelmintic, (Fenbendazole at the dose rate of 3gm per
animal). All the cows detected in estrus were allowed for artificial
insemination by frozen semen. Pregnancy was confirmed through
per rectum examination after 60 days of insemination. Blood
samples (20 ml) from each cow of all groups were collected during
fully conscious state by venipuncture of Jugular vein for the
studies of different biochemical parameters. Blood samples were
collected at day 0 (Just before administration of progesterone), at
the end of the drug administration, at the day of estrus and 25th
day after the artificial insemination. Group I was the control group
as animals were given normal saline but animals of group II were
given 50 mg progesterone daily for 15 days. In group III and IV, 100
mg and 150 mg progesterone was administered daily for 10 days.
In group III only two (33.33%), in group IV four (66.67) cows
exhibited estrus. In group V 250 mg progesterone was administered
for 7 days, all the six cows came in to estrus. After artificial
insemination one cow in group III, three cows in group IV and all
the cows in group V were conceived. At the end of pregnancy one
calf from group III two calves from group IV and only four calves
from group V were obtained as one cow from group IV and two
Cows from group V died due to severe pneumonia before
74
parturition, but were pregnant. Progesterone administration
increased the total serum protein significantly in group V that
received 250 mg daily for 7 days, compared to control and other
groups. Cholesterol is precursor of different steroidal hormone. Its
level can indicate circulating adequacy of these hormones
responsible for normal oestrus. Cholesterol level was significantly
(P<0.01) highest in case at oestrus period in group V compared to
control and other groups. There is certain level of inorganic
Phosphorus for estrogen secretion. In our study, there was no
supplementation of P in diet even there was significant (P<0.01)
increase of serum Phosphorus level in group V compared to control
and other groups. There was also significant (P<0.01) increase of
SGPT (ALT) and ALP level in blood serum of crossbred cows
showing the high physiological activity of enzymes in case of
progesterone administration in group V compared to control and
other groups. No animal was in milking stage, so the effect of
exogenous progesterone on milk production in cattle was not
observed. In conclusion, most preferred dose of progesterone for the
induction of oestrus cyclicity and fertility in anoestrus crossbred
cows was 250 mg daily for seven days. Although we did not achieve
the proper synchronizing time, so, it is suggested that in group V
instead of seven days we can enhance one or two days more
treatment with the same dose, although the conception and fertility
rate was up to the desired level.
Description
STUDY ON THE EFFECT OF DIFFERENT DOSES OF PROGESTERONE ON POSTPARTUM ANOESTRUS AND FERTILITY IN CROSSBRED CATTLE
Keywords
null