DETECTION AND PARTIAL GENETIC CHARACTERISATION OF A NOVEL VARIANT OF AVIAN NEPHRITIS VIRUS IN INDIAN POULTRY FLOCKS SHOWING DIVERSE CLINICAL SIGNS

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dc.contributor.authorGowthaman, Vasudevan
dc.contributor.authorSingh, Sambu Dha
dc.contributor.authorDhama, Kuldeep
dc.contributor.authorBarathidasan, Rajamani
dc.contributor.authorSrinivasan, Palani
dc.contributor.authorSaravanan, Sellappan
dc.contributor.authorGopalakrishnamurthy, Thippichettypalayam Ramasamy
dc.contributor.authorDeb, Rajib
dc.contributor.authorMathapati, Basavaraj
dc.contributor.authorRamakrishnan, Muthannan Andavar
dc.contributor.authorTANUVAS
dc.date.accessioned2018-07-13T10:42:07Z
dc.date.available2018-07-13T10:42:07Z
dc.date.issued2015-06
dc.descriptionTNV_AVH_2015_63(4)499-507en_US
dc.description.abstractAvian nephritis virus (ANV) infects poultry flocks worldwide, but no confirmed cases have been reported from India so far. In the current study, disease investigation was carried out in 21 broiler flocks at different parts of India with clinical signs of nephritis, uneven and stunted growth, diarrhoea, reduced body weight, and mortality up to 9.72%. Out of the 21 flocks screened, two were found positive for ANV in RT-PCR assay. BLAST analysis revealed that the ANV of Indian origin was closely related to ANV-1 strains reported from Japan, Hungary and China. However, comparison of a small portion (~12% of nucleotides, i.e. ~60 nts, common site for ANV-1 and ANV-3, position 2200–2260 of ORF 1a gene) of the Indian ANV sequence with ANV-3 sequences revealed 89–93% identities with different ANV-3 isolates. Phylogenetically, ANV-1 forms three clades, and the Indian ANV clustered under clade II. This study confirms the existence of ANV in Indian poultry flocks and is the first report on the molecular detection and genetic characterisation of ANV from India.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810060105
dc.keywordsAvian nephritis virus, clade II, astrovirus, RT-PCR, phylogenetic analysis, ORF 1a geneen_US
dc.language.isoenen_US
dc.pages499-507en_US
dc.relation.ispartofseries;4
dc.subjectVeterinary Scienceen_US
dc.titleDETECTION AND PARTIAL GENETIC CHARACTERISATION OF A NOVEL VARIANT OF AVIAN NEPHRITIS VIRUS IN INDIAN POULTRY FLOCKS SHOWING DIVERSE CLINICAL SIGNSen_US
dc.title.alternativeActa Veterinaria Hungaricaen_US
dc.typeArticleen_US
dc.volume63en_US
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