Biokinetics of Norfloxacin And Metronidazole in Goats
| dc.contributor.advisor | Dr. R.C. P. Singh | |
| dc.contributor.author | Kamleshwer Jha | |
| dc.date.accessioned | 2024-06-10T11:11:07Z | |
| dc.date.available | 2024-06-10T11:11:07Z | |
| dc.date.issued | 1992 | |
| dc.description.abstract | .The semi logarithmic plot of blood level time profile of MNZ obtained following single dose I/V administration € 20 mg/kg b.w. in febrile goats showed a biphasic decay suggesting "two compartment open model disposition Kinetics of MNZ in goats. 2. Evidence has been presented that MNZ when given I/V au a single dose è 20 mg/kg b.w. produced Coax (50.86 ± 0.63 8/ml) and Omin (1.35 ± 0.23 ug/ml) at 2 min and 4 h respectively and Other sustained upto 4 h of drug administration. 3. The Kinetic parameters determined evidenced that the meant 1/2 & value of MNZ was 1.034 0.071 h while the sean Cl value was 8.464 + 0.384 ml/kg/min which reflected relatively a faster rate of drug elimination; the mean Cl value was 6.810 + 0.280 ml/kg/ain reflec ting the biliary excretion of MNZ. 4. The mean Vd value was found to be 0.845 ± 0.980 L/kg indicating a wide distribution of MNZ in febrile goats; the other biokinetic parameters determined were 21 (3.118 + 1.557 -1), 12 (5.103 ± 1.257 h-¹) and X₂ (1.629 + 0.104 b¹) following I/V administration of NNZ 20 mg/kg b.w. | |
| dc.identifier.uri | https://krishikosh.egranth.ac.in/handle/1/5810210331 | |
| dc.language.iso | English | |
| dc.pages | 133 | |
| dc.publisher | Birsa Agricultural University, Ranchi | |
| dc.sub | Veterinary Pharmacology | |
| dc.theme | Biokinetics of Norfloxacin And Metronidazole in Goats | |
| dc.these.type | M.V.Sc. | |
| dc.title | Biokinetics of Norfloxacin And Metronidazole in Goats | |
| dc.type | Thesis |