EVALUATION OF ANTI RABIES VACCINAL EFFICACY IN FREE RANGING DOG POPULATION IN BENGALURU
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Date
2018-07
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KARNATAKA VETERINARY, ANIMAL AND FISCHERIES SCIENCE UNIVERSITY, BIDAR
Abstract
The present study was undertaken to evaluate the anti rabies vaccinal efficacy in
free ranging dog population in Bengaluru and comparison of an iELISA with RFFIT.
Serum samples from 250 free ranging dogs were collected for the study and tested by
RFFIT as well as iELISA. In all, 18 wards from the North and South zones of Bengaluru
were covered during the sample collection with the help of three NGOs, who claimed that
those animals were annually vaccinated. So, the post vaccinal efficacy was studied and it
was found that, out of 250 dogs 125 were having a protective anti rabies antibody titre by
RFFIT accounting for 50 per cent of seroconversion. Samples from North zone were
having a better seroconversion level (65.97%) than south zone of Bengaluru. By iELISA,
126 dogs showed a per cent positivity (PP) more than 57.09 (cut off) accounting for 50.4
per cent of post vaccinal seroconversion. A kappa value of >0.80 suggested a perfect
agreement between the results of RFFIT and iELISA. The sensitivity and specificity of
iELISA was found to be 94.4 per cent and 95.2 per cent respectively. This ELISA can be
used in large population surveys instead of RFFIT to overcome the disadvantages
associated with it. The present study emphases regular rabies vaccination followed by
seromonitoring of free ranging dogs in Bengaluru.