Evaluation Of Neuroleptanalgesia In Bovine
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Date
1990
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Birsa Agricultural University, Ranchi
Abstract
Three different combinations of neuroleptics and narcotic analgesics, constituting neuroleptanalgesics, were evaluated in 18 clinically healthy male cow calves, aged one to one and a half years. The animals were divided randomly into three groups of six animals each. In group I, combination of meperidine and promazine was injected. In group II, meperidine and diazepam were used together. In group III, Innovar-Vet was administered. Meperidine, promazine and diazepam were used at a dose rate of 12 mg, 3 mg and 1 mg per kilogram body weight respectively while Innovar-Vet 0.5 ml/10 kg by dow 1/v injection. Clinical observations, haematological and biochemical alterations including van den Bergh test were studied prior to the administration of neuroleptanalgesic and at 5, 15, 30, 60 and 120 minutes following induction of neuroleptanalgesia (NLA). Finally these parameters were evaluated at 24 hours of drug injection. Venous blood samples were collected at these time intervals. Mean arterial pressure, central venous pressure and heart rate vere measured at the periods specified above except the former two at 24 hours. For the estimation of cardiac output (a) arterial blood samples were collected after 1/v injection of Evans blue dye at 0 minute, and at 5, 30 and 120 minutes of administration of anaesthetics. The parameters related to a viz., cardiac index, stroke volume, total peripheral resistance, stroke index were computed with the help of other measured parameters like MAP, heart rate, body surface area, venous haematocrit etc.