Antioxidant Status in Curcumin Treated Rats in Experimental Mammary Carcinogenesis

Simple item page
dc.contributor.authorJalantha, P.
dc.contributor.authorBalachandran, C.
dc.contributor.authorPazhanivel, N.
dc.contributor.authorTANUVAS
dc.date.accessioned2016-07-19T13:29:14Z
dc.date.available2016-07-19T13:29:14Z
dc.date.issued2014-07
dc.description.abstractThe present study was carried out to evaluate the effect of curcumin on lipid peroxidation and antioxidant levels in DMBA (7, 12 Diemthyl Benanthracene) induced mammary carcinogenesis in rats. Twenty four Sprague-Dawley rats were equally distributed to control, DMBA, Tamoxifen (Standard drug) and curcumin groups. DMBA group showed significant (P<0.05) increase in lipid peroxidation and antioxidants superoxide dismutase (SOD) and catalase (CAT) levels besides reduced glutathione (GSH). Whereas, curcumin and Tamoxifen treated groups did not show any significant difference in lipid peroxidation and antioxidant status when compared to the control. Selective growth advantage of tumour cells was evident in the DMBA group and curcumin was able to prevent lipid peroxidation.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/68935
dc.language.isoenen_US
dc.publisherTamil Nadu Veterinary and Animal Sciences Universityen_US
dc.subjectAntioxidanten_US
dc.subjectCurcuminen_US
dc.subjectDMBAen_US
dc.subjectLipid peroxidationen_US
dc.subjectMammary carcinogenesisen_US
dc.titleAntioxidant Status in Curcumin Treated Rats in Experimental Mammary Carcinogenesisen_US
dc.title.alternativeIJVASR_43(4)_256-260_2014en_US
dc.typeArticleen_US
Files
Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
IJVASR_43(4)_256-260_2014.pdf
Size:
26.48 KB
Format:
Adobe Portable Document Format
Description:
Article
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
2.28 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Articles (1.Journal)