Pharmacokinetics of Enrofloxacin after Single Intravenous and Oral Bolus Administration in Broiler Chicken

The pharmacokinetics and bioavailability of enrofloxacin was compared in Cobb strain broiler chicken after intravenous and oral administration of enrofloxacin at the rate of 10mg.kg-1. The concentration of enrofloxacin at various time intervals in plasma was determined by HPLC and the pharmacokinetic parameters were calculated by non compartmental approach.