MOLECULAR EPIDEMIOLOGY OF FOOT AND MOUTH DISEASE VIRUS ISOLATES FROM ANDHRA PRADESH
| dc.contributor.advisor | SATYANARAYANA CHETTY, M(MAJOR) | |
| dc.contributor.advisor | SREENIVASULU, D | |
| dc.contributor.advisor | NARASA REDDY, G.V | |
| dc.contributor.advisor | HAFEEZ, Md. | |
| dc.contributor.advisor | ESWARA PRASAD, P | |
| dc.contributor.author | POORNIMA, M | |
| dc.date.accessioned | 2018-10-05T07:16:51Z | |
| dc.date.available | 2018-10-05T07:16:51Z | |
| dc.date.issued | 2007-03 | |
| dc.description | THESES | en_US |
| dc.description.abstract | ABSTRACT: Hither to the prophylactic vaccinations were being employed to protect the livestock from devastating FMD. Even then the occurrence of outbreaks were recorded. Hence, it has triggered the idea in the minds of the scientists to study the divergency of antigenicity of FMDV isolates which could be incorporated in the vaccination programmes. Hence, a modest attempt has been made on exposition of various dimensions of molecular epidemiology its applications and implications in disease management to evolve a suitable vaccine strain to cater the needs of farmers lest the occurrence will continue. The disease was recorded round the year from different agro-climatic zones of Andhra Pradesh, both among vaccinates and unvaccinated animals with maximum incidences in cattle species (1 7.45%) with type 0. The complementation of results of antigenic detection in clinical samples showed virus isolation as golden standard while RT-PCR as sensitive and specific where as ELISA as dependable diagnostic tool. The FMDV field isolates of diffment ago-climatic zones of Andhra Pradesh were catalogued and master banks were prepared. In FMDV detection of OP fluids from carrier animals more percentage of positives were recorded by RT-PCR technique (47.8%). The phylogenetic analysis of type 0 and A isolates, revealed circulation of genetically heterologus genotypes that might have antigenically drifted away from current vaccine strains in vogue. It has been extrapolated the genetic variancy of deduced amino acid sequences to understand the heterogenicity in antigenecity. The isolates recovered corroborated serological relatedness to vaccine strains OIND R2/75 and AIND 17/82 | en_US |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810074812 | |
| dc.keywords | MOLECULAR EPIDEMIOLOGY;FOOT;MOUTH DISEASE VIRUS;ISOLATES;ANDHRA PRADESH | en_US |
| dc.language.iso | en | en_US |
| dc.pages | 253 | en_US |
| dc.publisher | SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA | en_US |
| dc.sub | Veterinary Microbiology | en_US |
| dc.subject | null | en_US |
| dc.theme | MOLECULAR EPIDEMIOLOGY OF FOOT AND MOUTH DISEASE VIRUS ISOLATES FROM ANDHRA PRADESH | en_US |
| dc.these.type | Ph.D | en_US |
| dc.title | MOLECULAR EPIDEMIOLOGY OF FOOT AND MOUTH DISEASE VIRUS ISOLATES FROM ANDHRA PRADESH | en_US |
| dc.type | Thesis | en_US |