STUDIES ON HEMATO-BIOCHEMICAL PROFILE AND IMMUNE RESPONSIVENESS TO VACCINATION AGAINST FOOT AND MOUTH DISEASE IN MALNAD GIDDA CATTLE
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Date
2017-07
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KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR
Abstract
The present study was conducted to determine the reference values for
hematological parameters, biochemical parameters, female reproductive hormones in
Malnad Gidda cattle and the physiogenomic aspect such as genetic polymorphism at
MHC DRB3.2 loci and cellular immune responsiveness to FMD vaccination in Malnad
Gidda compared to Hallikar X HF crossbred cattle. Significantly lower values were
observed in young age groups of both sexes for TEC, hemoglobin, PCV, ESR, TLC,
eosinophil per cent, except MCV which was significantly higher in young age groups of
both sexes. However, No significant difference was observed for MCH, MCHC, and the
percentages of neutrophil, basophil, monocyte and lymphocyte. The levels of different
biochemical parameters such as the levels of serum total cholesterol, serum triglycerides,
HDL cholesterol, LDL cholesterol and VLDL cholesterol, serum total protein, serum
albumin, BUN, creatinine, β-hydroxy butyrate, blood glucose and the activities of AST
and ALT did not differ significantly among groups. Significant difference was not
observed between winter and summer seasons for any of the hematological and
biochemical profile taken up for the study among different groups. The reproductive
hormones such as 17β-estradiol and progesterone showed increasing and decreasing
pattern respectively, during estrous cycle in Malnad Gidda cattle similar to other breeds
of cattle. The two allelic variants MHC DRB3.2*117 and *219 present between Malnad
Gidda and Holstein Friesian crossbred cattle could be responsible for better cellular
immune responsiveness with significantly higher CD4 lymphocytes population to FMD
vaccination in Malnad Gidda cattle compared to Hallikar X HF crossbred cattle.