Molecular Diagnosis of Babesia canis Infection with Concurrent of Evans Syndrome in a Labrador Dog

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dc.contributor.authorSaravanan, M
dc.contributor.authorSelvaraj, P
dc.contributor.authorYogeshpriya, S, et al.
dc.contributor.authorTANUVAS
dc.date.accessioned2020-02-06T07:05:56Z
dc.date.available2020-02-06T07:05:56Z
dc.date.issued2019-12
dc.descriptionTNV_IJCMAS_2019_8(12)2522-2526en_US
dc.description.abstractClinical case is five years old female Labrador dog presented to Small Animal Medicine unit of TVCC, VCRI, Orathanadu. History is dullness and anorexia two days. Recurrent tick infestations, anemic and thrombocytopenic crisis were regularly. Vaccination and deworming were regularly. Physical examination revealed dullness, pale mucosa, vital parameters were normal and ticks on interdigital space and in ears were noticed. Distended abdomen, hepatosplenomegaly and petechial hemorrhage on ventral abdomen were observed. Hematology revealed anemia and thrombocytopenia. Negative for blood born parasites in peripheral blood smear. Serum biochemical and urine analysis found to be normal. Serum and EDTA blood were submitted for molecular testing. Flow cytometry revealed Immune-mediated hemolytic anemia (IMHA) and Immune-mediated thrombocytopenia (IMTP). MAT negative for leptospira. Babesia canis positive by PCR method at 394bp. Haematology alteration was studied before and after therapy. Ultrasonography revealed hepatosplenomegaly. Based on PCR and flow cytometry the case was confirmed Evans syndrome with Concurrent Babesia canis in a Labrador dog. Dog treated with Inj. Diminazene aceturate @ 3.5mg/kg IM single dose, Inj. Ringers lactate @ 100 ml IV, Inj. Ascorbic acid @ 5 ml IV, Inj. Vitamin B complex @ 1ml IV, Inj. Prednisone @ 0.5mg/ kg IM, Tab. Doxycycline @ 10mg/kg PO and Syrup. Thrombup @ 15 ml BID PO. Dog showed clinical improvement as well as hematology parameters.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810142598
dc.keywordsBabesia canis, IMTP, IMHA, Flow cytometry, Evans syndromeen_US
dc.language.isoenen_US
dc.pages2522-2526en_US
dc.relation.ispartofseries;1
dc.subjectVeterinary Scienceen_US
dc.titleMolecular Diagnosis of Babesia canis Infection with Concurrent of Evans Syndrome in a Labrador Dogen_US
dc.title.alternativeInternational Journal of Current Microbiology and Applied Sciencesen_US
dc.typeArticleen_US
dc.volume8en_US
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