IN VITRO AND IN VIVO EVALUATION OF MONTMORILLONITE TO AMELIORATE THE TOXICOLOGICAL EFFECTS OF AFLATOXIN B1 IN BROILERS
| dc.contributor.advisor | Dr. MALATHI, V. | |
| dc.contributor.author | ISMAIL ZABIULLA A | |
| dc.date.accessioned | 2022-08-26T05:35:56Z | |
| dc.date.available | 2022-08-26T05:35:56Z | |
| dc.date.issued | 2019-01 | |
| dc.description.abstract | A study was conducted to evaluate In vitro binding efficiency of binder (montmorillonite) for aflatoxin B1 (AFB1) and its ameliorative effect in commercial broiler chicken for 42 days. The binder was added to compounded broiler feed at three levels, 0.1%, 0.2% and 0.5% and AFB1 was added at approximately 0.5 ppm level to all the flasks. Binding ability was tested at pH 4.5 and 6.5. At pH 4.5, motmorillonite showed higher binding (46.47 %) at 0.2% level than other other two levels of the binder. However, no significant difference was recorded in binding per cent between different levels of the binder at either of the pH. In the trial, broiler chicks were randomly assigned to one of the three dietary treatments: T1 (basal diet), T2 (control + 0.5 ppm AFB1) and T3 (control + 0.5 ppm aflatoxin + 0.2% montmorillonite). The aflatoxin challenge was successful with depression in growth performance, elevated levels of aspartate aminotransferase (AST) and Gamma-glutamyl transferase (GGT), organ enlargement and immuno-suppression in challenged broilers compared to the Control. In relation to the T2 group, T3 group showed, significant (P<0.05) improvement in the final weight, feed efficiency and FCR of broilers. There were no significant effect of diets on the levels of AST, GGT and ALP. However, globulin level was significantly (P<0.05) higher in T3 when compared to T2 group. The se | en_US |
| dc.identifier.uri | https://krishikosh.egranth.ac.in/handle/1/5810186729 | |
| dc.language.iso | English | en_US |
| dc.pages | 192 | en_US |
| dc.publisher | KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR | en_US |
| dc.sub | Poultry Science | en_US |
| dc.theme | POULTRY SCIENCE | en_US |
| dc.these.type | M.V.Sc. | en_US |
| dc.title | IN VITRO AND IN VIVO EVALUATION OF MONTMORILLONITE TO AMELIORATE THE TOXICOLOGICAL EFFECTS OF AFLATOXIN B1 IN BROILERS | en_US |
| dc.type | Thesis | en_US |