Exploration of Immunomodulatory Effect of Nilavembu Kudineer Chooranam against Newcastle Disease Virus in Backyard Chicken
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Date
2017
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Abstract
Nilavembu Kudineer Chooranam (NKC) was subjected to preliminary phytochemical screening and its
immunomodulatory activity was assessed in sixty day-old unsexed backyard chicken divided into six
treatment groups of ten each. T1 served as control, T2 was vaccine control, T3 was positive control treated
with levamisole, T4 - T6 were administered Nilavembu Kudineer Chooranam (NKC) @ 0.5, 1.0 and
2.0mL/kg body weight respectively for five days before vaccination. The birds (T2 - T6) were vaccinated
with oral pellet vaccine (D58 strain) against Newcastle disease virus at the end of 1st, 4th and 8th week and
HI titre was evaluated at the end of 4th, 8th, 12th and 16th week in all the groups. Throughout the
experiment, the group pretreated with NKC @ 1.0mL/kg (T5) had shown significantly higher titre when
compared to vaccine control (T2). The positive control (T3) was numerically better than vaccine control
(T2) throughout the study. At the end of 12th and 16th week, the titre of positive control was significantly
less than T5. The results revealed that NKC when used @ 1.0mL/kg for 5 days in drinking water before
immunization resulted in improvement in immune response in backyard chicken.
Description
TNV_JPP_2017_6(6)749-751
Keywords
Veterinary Science