PATHOLOGICAL STUDIES OF OCHRATOXICOSIS AND ITS AMELIORATION USING DIATOMACEOUS EARTH AND VITAMIN E IN BROILER CHICKENS

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dc.contributor.advisorM. L. SATYANARAYANA
dc.contributor.advisorG. V. SUDHAKAR RAO
dc.contributor.advisorH. D. NARAYANASWAMY
dc.contributor.advisorSUGUNA RAO
dc.contributor.advisorS. YATHIRAJ
dc.contributor.advisorS. G. RAMACHANDRA
dc.contributor.authorDHEERENDRA NAIK
dc.date.accessioned2019-08-14T09:41:21Z
dc.date.available2019-08-14T09:41:21Z
dc.date.issued2016-05
dc.description.abstractThe study was conducted to evaluate the pathological and immunosuppressive effect of ochratoxin (OA) in broiler chicken and its amelioration using diatomaceous earth (DAE). Experimental ochratoxicosis was induced in broilers with 1 ppm and the ameliorating effects of DAE @ 2000mg/kg feed and Vitamin E 80ml/kg of feed was studied for 35 days. Feeding of ochratoxin caused significant reduction in the body weight gain and feed efficiency. Supplementation of DAE and Vitamin E showed improvement in performance parameters. Ochratoxicosis showed significant increase in relative weights of liver, kidneys and spleen whereas, the weights of bursa of Fabricius and thymus was reduced. Significant improvement in the organ weight was observed in DAE Vitamin E and their combinations supplemented birds. The serum levels of total protein and albumin were significantly lowered whereas, creatinine, AST, ALT and ALP were higher in toxin fed birds. The HI titres against NDV and antibodies against IBD, DAE and Vitamin E supplementation showed improvement in HI titre, against ND and antibodies against IBDV. Microscopic lesions, characteristic to ochratoxicosis were prominent in kidneys, liver and lymphoid organs. Supplementation of DAE and Vitamin E reduced the severity of lesions in these organs. Dietary inclusion of ochratoxin caused hepato-renal and immunotoxicity in birds. However, supplementation with DAE and Vitamin E was helpful in ameliorating the adverse effects of ochratoxicosis in broilers.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810121758
dc.keywordsOchratoxin, broiler chicken, Diatomaceous earth, Vitamin E, Pathology, Immune responseen_US
dc.language.isoenen_US
dc.pages195en_US
dc.publisherKARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDARen_US
dc.subVeterinary Pathologyen_US
dc.subjectnullen_US
dc.themeVETERINARY PATHOLOGYen_US
dc.these.typePh.Den_US
dc.titlePATHOLOGICAL STUDIES OF OCHRATOXICOSIS AND ITS AMELIORATION USING DIATOMACEOUS EARTH AND VITAMIN E IN BROILER CHICKENSen_US
dc.typeThesisen_US
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