Seminal Plasma Osteopontin: A Marker for Potential Fertility in Dogs

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dc.contributor.authorAbedin, SN
dc.contributor.authorLeela, V
dc.contributor.authorDevendran, P, et al.,
dc.contributor.authorTANUVAS
dc.date.accessioned2021-12-09T07:09:44Z
dc.date.available2021-12-09T07:09:44Z
dc.date.issued2021-07
dc.descriptionTNV_IJAR_2021_55(7)758-762en_US
dc.description.abstractABSTRACT Background: Osteopontin (OPN) is an extracellular matrix protein with multifunctions and has been identified in the reproductive tract of both males and females. OPN from the seminal plasma (SP) has been closely associated with male fertility in several domestic animals. Different isoforms of OPN has been identified in the SP and sperm membrane in dogs but with unknown functions. The current study investigated the comparison of key canine sperm microscopic parameters and SP markers between dogs exhibiting different fertility potential. Methods: In this investigation during 2018-2019, 21 dogs coming for breeding soundness examination were selected and divided into fertile (Group I) and hypofertile (Group II). Evaluation included assessment of sperm microscopic characteristics and estimation of OPN, Malondialdehyde (MDA), Catalase (CAT), Glutathione peroxidase (GPx) and Superoxide dismutase (SOD) concentration in the SP. Result: The OPN level showed positive correlation with all the sperm evaluated characteristics (p<0.01). Linear regression analysis depicted a significant (p<0.001) influence of OPN on the evaluated sperm characteristics. These findings suggest that OPN in the SP along with the microscopic characteristics of the spermatozoa can be used as a potential fertility marker in discriminating fertile from the hypofertile ones.en_US
dc.identifier.urihttps://krishikosh.egranth.ac.in/handle/1/5810178909
dc.keywordsDogs, Fertile, Hypofertile, Malondialdehyde, Osteopontin, Seminal plasma.en_US
dc.language.isoEnglishen_US
dc.pages758-762en_US
dc.relation.ispartofseries;7
dc.subjectVeterinary Scienceen_US
dc.titleSeminal Plasma Osteopontin: A Marker for Potential Fertility in Dogsen_US
dc.title.alternativeIndian Journal of Animal Researchen_US
dc.typeArticleen_US
dc.volume55en_US
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