STUDIES ON THE EFFECT OF ROMIFIDINE PREMEDICATION ON KETAMINE INDUCTION AND ISOFLURANE MAINTENANCE GENERAL ANAESTHESIA IN CATTLE
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Date
2018-10
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KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR
Abstract
The study was conducted in cattle to standardize the Romifidine-KetamineIsoflurane anaesthetic protocol. During the present study the following parameters were
assessed: A. Physiological parameters like rectal temperature, heart rate, pulse rate,
respiratory rate, Electrocardiogram, Mean arterial pressure. B. Hematological parameters
viz., total erythrocyte count (TEC), hemoglobin concentration (Hb), packed cell volume
(PCV), total leukocyte count (TLC), differential leukocyte count (DLC), C. Biochemical
parameter like aspartate aminotransferase (AST), blood urea nitrogen, serum creatinine
and blood glucose. D. Blood gas like PaO2, PaCO2 and blood pH analyses were also
done. The quality of sedation, induction and anaesthesia were assessed based on the signs
shown by the animals during the period of anaesthesia. The anaesthetic parameters such
as the onset of sedation, induction time, attaining surgical plane of anaesthesia, duration
of anaesthesia, recovery time, extubation time, time for sternal recumbency and time for
unassisted standing were assessed during the period of anaesthesia. Results revealed, in
all the animals there were non-significant minor alterations in physiological,
hematological and biochemical parameters, whereas some significant changes were
observed in PaO2, PaCO2 and were returned to normalcy during recovery period. The
induction and recovery of anaesthesia were faster and rapid respectively in the present
study. Findings were suggestive of Romifidine-Ketamine-Isoflurane anaesthetic protocol
employed in the study was safe and effective. In conclusion, the general anaesthesia in
cattle may be carried out safely and effectively by using the anaesthetic protocol
employed in the present study.The study was conducted in cattle to standardize the Romifidine-KetamineIsoflurane anaesthetic protocol. During the present study the following parameters were
assessed: A. Physiological parameters like rectal temperature, heart rate, pulse rate,
respiratory rate, Electrocardiogram, Mean arterial pressure. B. Hematological parameters
viz., total erythrocyte count (TEC), hemoglobin concentration (Hb), packed cell volume
(PCV), total leukocyte count (TLC), differential leukocyte count (DLC), C. Biochemical
parameter like aspartate aminotransferase (AST), blood urea nitrogen, serum creatinine
and blood glucose. D. Blood gas like PaO2, PaCO2 and blood pH analyses were also
done. The quality of sedation, induction and anaesthesia were assessed based on the signs
shown by the animals during the period of anaesthesia. The anaesthetic parameters such
as the onset of sedation, induction time, attaining surgical plane of anaesthesia, duration
of anaesthesia, recovery time, extubation time, time for sternal recumbency and time for
unassisted standing were assessed during the period of anaesthesia. Results revealed, in
all the animals there were non-significant minor alterations in physiological,
hematological and biochemical parameters, whereas some significant changes were
observed in PaO2, PaCO2 and were returned to normalcy during recovery period. The
induction and recovery of anaesthesia were faster and rapid respectively in the present
study. Findings were suggestive of Romifidine-Ketamine-Isoflurane anaesthetic protocol
employed in the study was safe and effective. In conclusion, the general anaesthesia in
cattle may be carried out safely and effectively by using the anaesthetic protocol
employed in the present study.