ROMIFIDINE SEDATION WITH KETAMINE OR PROPOFOL INDUCTION FOR ISOFLURANE ANAESTHESIA IN GOATS
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Date
2018-07
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KARNATAKA VETERINARY ANIMAL AND FISHERIES SCIENCE'SUNIVERSITY, BIDAR-585226
Abstract
The study was carried out to evaluate the feasibility of romifidine sedation for
ketamine or propofol-isoflurane general anaesthesia for various surgeries in goats. The
study was carried out in 12 clinical cases of goats presented for various surgical procedures
and were randomly divided into two groups consisting of six goats in each group. The goats
of both the groups were premedicated with romifidine hydrochloride (50µg/kg, IV). After
ten minutes the animals of group I and II were induced with ketamine (6 mg/kg, IV) and
propofol (6mg/kg IV) respectively then anaesthesia maintained with isoflurane (1-2%) in
both the groups. Onset of sedation, down time to sternal recumbency were faster in both
the groups. Ketamine-isoflurane was associated with better haemodynamic stability in
comparison to propofol-isoflurane. However, propofol induction had advantage of
excellent sedation and muscle relaxation. Haemoglobin and total erythrocyte count
decreased non-significantly, whereas, packed cell volume and total leukocyte count
decreased significantly at maximum depth of anaesthesia in both the groups. All the
haemato-biochemical changes were within physiological limits. The preanesthetic and the
general anaesthetic combinations followed in both the groups provided satisfactory
surgical plane of anaesthesia and were ideal and safe to perform major surgeries in goats
without any complications.
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