COMPARATIVE EVALUATION OF DIFFERENT ANAESTHETIC PROTOCOLS FOR STANDING SEDATION IN BUFFALOES
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Date
2023-04
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SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA
Abstract
The present study “comparative evaluation of different anaesthetic protocols for
standing sedation in buffaloes” was undertaken to standardize the anaesthetic doses and
combinations and to evaluate the efficacy of Butorphanol + Xylazine + Ketamine vs
Butorphanol+ Dexmedetomidine + Ketamine with reference to clinical, physiological,
biochemical and haematological parameters. The group I (6) animals were sedated with
butorphanol @ 0.01 mg/kg B. wt, xylazine @ 0.02 mg/kg B. wt and ketamine @ 0.04
mg/kg B. wt I/V whereas in group II (6), animals were sedated with butorphanol @ 0.01
mg/kg B. wt, dexmedetomidine @ 1 µg/kg B. wt and ketamine @ 0.04 mg/kg B. wt
I/V. Horn amputation was performed under sedation followed by cornual nerve block
and ring block.
In group I, 66.67% of animals had shown mild salivation and 33.33% of animals
showed very mild salivation. In group II, 66.67% of animals had shown moderate
salivation and 33.33% of animals showed mild salivation. In group I, 83.33% of the
animals showed lowering of the head whereas, all animals in group II showed lowering
of the head. All the animals in both the groups had shown drooping of their upper
eyelids and were aware of their surroundings. 50% of the animals in both groups had
shown snoring.
In group I, 83.33% of the animals had shown a good degree of sedation
followed by 16.67% of animals with a mild degree of sedation; whereas in group II,
66.67% of the animals had shown a profound degree of sedation followed by 33.33% of
animals with a good degree of sedation. Group I had shown a highly significant increase
(P<0.01) in the meantime of onset of sedation compared to that of group II, whereas
group II had shown a highly significant increase (P<0.01) in the duration of sedation
compared to that of group I. Group II had shown a better analgesic effect compared to
that of group I.
Physiological parameters like rectal temperature, respiratory and pulse rates
fluctuated within the normal physiological range in both the groups. The haemoglobin,
TEC, TLC, glucose, creatinine, ALT, AST and cortisol values fluctuated within the
normal physiological range in both the groups.
Out of six animals in group I, 83.33 % (5) of animals had shown good recovery
followed by 16.67 % (1) of animals with excellent quality of recovery; whereas in
group II, all the animals had shown an excellent quality of recovery i.e., group II was
superior to group I. Butorphanol-Dexmedetomidine-Ketamine protocol showed quick
onset, profound degree of sedation, better analgesia and excellent quality of recovery
with longer duration of action than Butorphanol-Xylazine-Ketamine. It can be
concluded that both protocols employed in the present study were safe and effective for
standing sedation in buffaloes.