COLLAGEN AND SILICONE EXTRACELLULAR MATRICES EMBEDDED WITH AUTOLOGOUS PLATELET RICH PLASMA FOR CUTANEOUS WOUND HEALING IN HORSES
Loading...
Date
2021
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The present work was done to study the utility of collagen and silicone extracellur matrices embedded with autologous platelet rich plasma for cutaneous wound healing in horses. The study was conducted in twelve clinical cases (N=12) with cutaneous wound in apparently healthy horses which were brought to the Large Animal Outpatient Unit of Madras Veterinary College Teaching Hospital, Chennai-07.
The clinical cases of horses were divided into two groups of six animals each (N=6). Group I animals were treated with collagen extracellular matrices embedded with autologous platelet rich plasma and group II animals were treated with silicone foam dressing embedded with autologous platelet rich plasma.
The parameters studied during the post treatment period were clinical/macroscopical observation (colour of wound, wound exudates, presence of crest, granulation tissue, and skin sensibility), wound planimetry (percentage of
epithelialization, percentage of contraction, percentage of wound healing), haemato-biochemical analysis, histological evaluation, wound exudate analysis and assessment of vascularity by ultrasonagraphy for wound healing. These parameters were studied for 0, 5, 15, 30 and 45th day of post treatment period.
Macroscopical evaluation of wound showed no apparent changes in both the groups.