CHARACTERIZATION OF GENOME-WIDE SNPs AND ANNOTATION OF HEAT TOLERANCE GENES IN INDIGENOUS CATTLE BREEDS OF TAMIL NADU
Loading...
Date
2022
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Cattle play a major role in agriculture in developing countries. Cattle
breeds in India are well-adapted to the tropical climate, resistant to most of the
tropical diseases and survive well in low input system. The genetic improvement
of native cattle has been implemented in few breeds by selective breeding based
on their phenotypic characteristics. Recently, genomic technologies like SNP
genotyping and marker-assisted selection have been used to select animals based
on their genetic makeup for which, identification of specific SNPs associated with
economic traits is necessary. The SNP arrays currently used for genotyping are
biased towards taurine cattle, which indicates the need to discover a substantial
number of SNPs across many indigenous breeds, belonging to various
geographical regions, to build new high-density SNP arrays for unbiased
genotyping and subsequent genomic selection for economically important traits in
indigenous cattle. Our study was aimed at identifying a greater number of SNPs
and indels in the genome of five indigenous cattle breeds of Tamil Nadu, viz.
Kangayam, Umblachery, Pulikulam, Bargur and Alambadi, which are known for
their draught ability, through whole-genome sequencing and validation of SNPs in
heat tolerance genes.