STUDIES ON THE HYPOGLYCAEMIC EFFECTS OF STRYCHNOS POTATORUM AND ACACIA ARABICA ON ALLOXAN DIABETES IN RABBITS
Loading...
![Thumbnail Image](assets/images/Item.jpg)
Date
1981
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
1. Effect of Strychnos potatroum, Acacia arabica and tolbutamide
were studied in rabbits rendered diabetic by intravenous
administration of alloxan at a dose rate of 120mg./Kg body weight.
2. On the seventh day after alloxan administration, Strychnos
potatorum seed powder (0.5gm.jkg), Acacia arabica bark decoction
(20 ml/Kg) and tolbutamide (Rastinon 0.25gm/Kg) were administered
by stomach tube to diabetic rabbits fasted for 18 hours. Blood
samples were collected at 0, 1, 2, 3, and 4 hours.
3. Strychnos potatorum, Acacia arabica and tolbutamide produced
significant reduction in blood glucose level as compared to the
control, maximum reduction being two hours after administration.
In the first hour Strychnos potatorum produced a rise in blood sugar
level and subsequently a fall below the initial level.
Description
TNV_CRN_1981_10(1)1-5
Keywords
Veterinary Science