Evaluation Of Safety And Humoral Antibody Response Of Newcastle Disease Oral Pellet Vaccine In the Field Condition
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Date
2021-01
Journal Title
Journal ISSN
Volume Title
Publisher
TANUVAS, Chennai
Abstract
Newcastle Disease (ND) is a highly infectious disease of poultry causing huge economic
loss to the poultry farmers. Newcastle Disease is controlled by vaccination of commercial
or backyard poultry using inactivated or live ND vaccines. In the present study, safety and
humoral antibody response in birds vaccinated with Newcastle disease virus oral pellet
vaccine (NDV OPV) was studied in field conditions. A total of 300 backyard poultry (n=100/
farm) from three different farms were vaccinated with NDV OPV. The vaccinated birds were
monitored for any adverse reactions or mortality up to 28 days post vaccination (dpv). There
were no untoward reactions or mortality in the vaccinated birds in all the three farms up
to 28 dpv. Blood samples (n=8/farm) were collected randomly from vaccinated birds on 0
and 28 dpv in each farm and were subjected to heamagglutination inhibition (HI) test. The
mean HI titre was 66, 56 and 25 in farm 1, farm 2 and farm 3 respectively at 28 dpv. All the
vaccinated birds had protective HI titre of ≥16 at 28 days post vaccination. In conclusion,
Newcastle disease virus oral pellet vaccine (NDV OPV) is safe and induces good protective
humoral antibody response and can be used to control ND in backyard poultry.
Description
TNV_IJVASR_50(1)_Jan-Feb,2021_32-37
Keywords
Veterinary Science, Veterinary Microbiology