CLINICO-DIAGNOSTIC AND THERAPEUTIC STUDIES ON RENAL DISEASE IN DOGS
Loading...
Files
Date
2020-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA
Abstract
During the study period of two years, the occurrence of renal diseases in dogs accounted
up to 3.40 per cent in. Among the affected dogs, 18.24 per cent suffered with acute kidney
injury, whereas 81.76 per cent were of chronic kidney disease. Kidney diseases were more
prevalent in male dogs, aged above 8 years and the occurrence was more in Pomeranian
(30.82%).
In the affected dogs, the clinical presentation varied from asymptomatic to typical
clinical signs. Detailed haemato- biochemical examination and imaging studies performed
in 128 dogs revealed that, 25 dogs were affected with AKI and 103 dogs had CKD.
The dogs with CKD were further categorized into four stages based on SDMA
values as stage I, II, III and IV. The SDMA values in the affected dogs ranged from 14 to
152 μg/dL. Sub staging of CKD dogs was done based on UPC and Blood pressure.
Significant difference (P0.05) was noticed in mean values of PI and RI in
acute kidney injury and chronic kidney disease stage I and II with the healthy control while
the same in chronic kidney disease stage III and IV varied significantly (P0.05) was noticed in mean values of LA/Ao and M
mode echocardiographic findings in dogs with acute kidney injury which varied
significantly (P<0.05) in chronic kidney disease.
Therapy was initiated in dogs with kidney diseases by using herbal antioxidant,
diuretic, phosphate binders, antibiotics, diuretic, ACE inhibitors, nutritional therapy,
haematinics, fluid therapy along with specific treatment and were monitored for a period
of 3 months.
The survival percentage of dogs with acute kidney injury (Group I) was 84.00%
per cent (21/25). The survival percentage was 100.00 per cent in Group IIa (17/17) and
IIb (15/15) i.e., chronic kidney disease stage I and stage II, where as it was 80.00 per cent
(20/25) in CKD stage III (Group IIc) and 56.00 per cent (26/46) in chronic kidney disease
stage IV (Group IId).
Significant difference (p<0.05) was recorded in the SDMA/creatinine
ratio(9.20±0.18 in survivors vs 12.07 ± 0.42 in non survivors, BUN ( 82.53±1.84 mg/dL
vs 148.62±12.82mg/dL), product of calcium and phosphorus(58.22±2.02 vs 89.32±1.92),
sodium to potassium ratio (39.42±1.02 vs 48.93±1.32) , UPC (1.92±0.22 vs 3.86±0.52 )
and resistive index (0.62±0.56 vs 0.74±0.24) between survivors and non survivors
Description
THESES