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Assam Agricultural University, Jorhat

Assam Agricultural University is the first institution of its kind in the whole of North-Eastern Region of India. The main goal of this institution is to produce globally competitive human resources in farm sectorand to carry out research in both conventional and frontier areas for production optimization as well as to disseminate the generated technologies as public good for benefitting the food growers/produces and traders involved in the sector while emphasizing on sustainability, equity and overall food security at household level. Genesis of AAU - The embryo of the agricultural research in the state of Assam was formed as early as 1897 with the establishment of the Upper Shillong Experimental Farm (now in Meghalaya) just after about a decade of creation of the agricultural department in 1882. However, the seeds of agricultural research in today’s Assam were sown in the dawn of the twentieth century with the establishment of two Rice Experimental Stations, one at Karimganj in Barak valley in 1913 and the other at Titabor in Brahmaputra valley in 1923. Subsequent to these research stations, a number of research stations were established to conduct research on important crops, more specifically, jute, pulses, oilseeds etc. The Assam Agricultural University was established on April 1, 1969 under The Assam Agricultural University Act, 1968’ with the mandate of imparting farm education, conduct research in agriculture and allied sciences and to effectively disseminate technologies so generated. Before establishment of the University, there were altogether 17 research schemes/projects in the state under the Department of Agriculture. By July 1973, all the research projects and 10 experimental farms were transferred by the Government of Assam to the AAU which already inherited the College of Agriculture and its farm at Barbheta, Jorhat and College of Veterinary Sciences at Khanapara, Guwahati. Subsequently, College of Community Science at Jorhat (1969), College of Fisheries at Raha (1988), Biswanath College of Agriculture at Biswanath Chariali (1988) and Lakhimpur College of Veterinary Science at Joyhing, North Lakhimpur (1988) were established. Presently, the University has three more colleges under its jurisdiction, viz., Sarat Chandra Singha College of Agriculture, Chapar, College of Horticulture, Nalbari & College of Sericulture, Titabar. Similarly, few more regional research stations at Shillongani, Diphu, Gossaigaon, Lakhimpur; and commodity research stations at Kahikuchi, Buralikson, Tinsukia, Kharua, Burnihat and Mandira were added to generate location and crop specific agricultural production packages.

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2019 - 201922020 - 20211
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Subject: Veterinary Surgery and Radiology × Start date: 2019 × Type: Thesis × Thesis Type: Ph.D ×
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    ThesisItemOpen Access
    CLINICAL, CARDIOPULMONARY, HAEMATOBIOCHEMICAL AND IMMUNOLOGICAL EFFECTS OF ISOFLURANE, PROPOFOL AND KETAMINE IN GLYCOPYRROLATE, DEXMEDETOMIDINE AND BUTORPHANOL PREMEDICATED DOGS
    (College of Veterinary Science, Assam Agricultural University, Khanapara, Guwahati, 2019-07) BAYAN, HITESH; Sarma, Kushal Konwar
    The study was conducted to evaluate the clinical, cardiopulmonary, haematobiochemical and immunological effects of isoflurane, propofol and ketamine anaesthesia in glycopyrrolate, dexmedetomidine and butorphanol premedicated dogs. The study was carried out on twenty four number of female dogs presented for elective ovariohysterectomy. The animals were randomly divided into four groups (A, B, C and D) comprising of six animals each. The animals in all the groups were administered with glycopyrrolate 0.01 mg/kg IM followed 15 min by dexmedetomidine 5μg/kg IV and Butorphanol 0.1mg/kg IV. Two min after administration of dexmedetomidine and butorphanol, induction of anaesthesia was done with propofol IV till effect in Groups A and B and with ketamine IV till effect in Groups C and D. The anaesthesia was maintained with isoflurane in Groups A and C. In Groups B and D, the anaesthesia was maintained with continuous rate infusion of propofol 0.2-0.5 mg/kg/min and ketamine 0.002-0.02 mg/kg/min, respectively. The induction doses of propofol were recorded as 0.67±0.07 mg/kg in Group A and 0.68± 0.06 mg/kg in Group B where as the induction doses of ketamine were recorded as 2.55± 0.24 mg/kg in Group C and 2.63±0.26 mg/kg in Group D. Induction was quick and smooth in all the groups enabling easy endotracheal intubation. The analgesia, muscle relaxation and depth of anaesthesia were sufficient for performing major abdominal operations. The mean maintenance dose (mg/kg/min) of propofol and ketamine were recorded as 0.24±0.01 and 0.013.17±0.60 respectively in groups B and D. The mean vaporizer settings (%) for isoflurane were recorded as 1.34±0.06 and 1.28±0.07, respectively in Groups A and C. The recovery time was shortest in Group A and longest in Group D. The quality of recovery was better in Groups B, A & C in sequence as compared to Group D. The changes in the clinical parameters remained within the physiological limits in all the groups. Changes in blood pressure and ECG remained within the physiological limit in all the groups. The respiratory parameters were well maintained with isoflurane but the oxygen saturation values were near the critical level in Group D. The changes in haematological (haemoglobin, TEC, TLC, PCV, granulocytes, platelet and DLC) and biochemical (serum glucose, serum total protein, GGT, ALP, BUN, serum creatinine and LDH) parameters were found to be within physiological limits in all the animals. The immunological parameters exhibited immune suppressions but were transient in nature in all the groups. To conclude, all the anaesthetic combinations were safe and effective for major abdominal surgery in dogs. However, the respiratory parameters were more stable with inhalation agents used for maintenance and near the border line in particularly with ketamine CRI. The CRI with propofol was found to be better than with ketamine for maintenance in dogs premedicated with dexmedetomidine and butorphanol.
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    ThesisItemOpen Access
    SILK BASED OSTEOINDUCTIVE SCAFFOLD FOR BONE TISSUE ENGINEERING
    (College of Veterinary Science, Assam Agricultural University, Khanapara, Guwahati, 2019-07) SHARMA, MANAV; Sarma, Kushal Konwar
    B. mori silk cocoons were processed by established state of the art protocol to obtain silk fibroin aqueous solution, which was further used for scaffold fabrication. Three types of highly porous three dimensional sponge feel scaffolds were fabricated using traditionally used herbal based medicine i.e. Curcumin & Cissus quadrangularis. They are Silk Fibroin scaffold (SF), Silk Fibroin blended with Curcumin (CuSF) and Silk Fibroin blended with Cissus quadrangularis extract (CqSF). FESEM revealed highly porous scaffold with homogenously distributed interconnected pores in all types of scaffolds with pore ranging from 45.73-121.1 μm, 42.37-137.8 μm and 50.95-103.4 μm for SF, Cu-SF and Cq-SF respectively. The average porosity for each scaffold obtained were 88.57 %, 91.47 %, 93.03 % for SF, CuSF, CqSF respectively. Swelling and Water Holding Capacity were calculated to be 4.14%, 2.14% and 2.43% and 89.37 %, 92.04 % and 93.75 % for SF, CqSF, CuSF respectively. 42 numbers of New Zealand White rabbits were procured from authorized supplier for the study after obtaining IAEC clearance. Scaffolds were implanted into critical size radius bone defect (1.5 to 2 cm) following state of the art anaesthetic protocol. 0.5ml autologous bone marrow (BM) was collected and seeded immediately after collection for each type of scaffold considering as a separate animal group. Satisfactory clear radiographic union could be observed as early as by 30th day and initiation of remodeling by 60th day for Cu-SF & Cu-SF-BM groups. SF & SF-BM group radiographic union was evidence by 60th day but with a less opaque area compared to Cu- SF & Cu-SF-BM group. Relatively satisfactory radiographic union was also observed by the end of the observation period in Cq-SF group. In contrast, Cq-SF-BM group revealed no radiographic union even up to the end of the observation period. Histological samples were collected at the end of the radiographic observation (90th day) and processed for H & E staining. New blood vessel, marrow cells and new bone tissue could also be demonstrated for both Cu-SF & Cu-SF-BM group. In both SF & SF-BM group fibrous connective tissue could be visualized, along with cartilaginous tissue in SF-BM group. In Cq-SF group also along with fibrous connective tissue with new boney tissue could be demonstrated. But in Cq-SF-BM group fibrous connective tissue could only be demonstrated. Finally it could be concluded that B. mori silk fibroin could effectively be used and biofunctionalized with traditionally known fracture healing herbal based ingredients for bone tissue engineering application as evidence by satisfactory radiographic and histological findings in Cu-SF, Cu-SF-BM and Cq-SF groups.
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    ThesisItemOpen Access
    SURGICAL STERILIZTION OF CAPTIVE SAMBAR DEER (Cervus unicolor)
    (2021-06) DEKA, DEEPJYOTI; Sarma, Kushal Konwar
    Eighteen clinically healthy captive sambar stags, weighing 80-110kgs were divided into three groups, containing of 6 calves in each group, where group-A received xylazine hydrochloride @ 1.5 mg/kg and and ketamine hydrochloride @ 2.5 mg/kg bodyweight intramuscularly, group-B received xylazine hydrochloride @ 1.5 mg/kg and tiletamine-zolazepam @ 2.5mg/kg bodyweight intramuscularly and group-C received xylazine hydrochloride @ 1.5 mg/kg + and azaperone @ 1mg/kg bodyweight intramuscularly. The induction time and recovery time were 11.83 ± 1.07 and 36.66 ± 0.95 minutes respectively in group-A, 5.16 ± 0.30 and 59.83 ± 2.40 minutes respectively in group-B and 7.16 ± 0.30 and 45.25 ± 1.09 minutes respectively in group-C. Induction and recovery were smooth. Muscle relaxation and analgesia were good. Animals of all group exhibited signs of sedation with lowering of head, occasional bellowing, heavy upper eyelid (drowsiness), onset of salivation, reduced tail movement and signs of staggering. Polyuria was observed at recovery. Heart rate decreased significantly (p0.05) difference in all the three groups. Respiratory tidal volume increased non-significantly (p>0.05) and respiratory minute volume showed high significant (p0.05) in the group-A, B but in group-C, SpO2 increased significantly (p0.05) in group-A, B and C. Highly significant (p0.05) in group-A and B and decreased significantly (p0.05) increase group-A and significant increase in group-B and C. Based on the findings of the study, xylazine - Zoletil® 100 anaesthesia produced a balanced anaesthesia with excellent analgesia and muscle in sambar stags followed by the xylazine-azaperone. Caudectomy has got advantageous over vasectomy in terms of mean ABSTRACT time required to perform the surgery. No such behavioral and physical changes were observed among the operated sambar stags over a period of 1 year during the study.