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Anand Agricultural University, Anand

Anand Agricultural University (AAU) was established in 2004 at Anand with the support of the Government of Gujarat, Act No.(Guj 5 of 2004) dated April 29, 2004. Caved out of the erstwhile Gujarat Agricultural University (GAU), the dream institution of Sardar Vallabhbhai Patel and Dr. K. M. Munshi, the AAU was set up to provide support to the farming community in three facets namely education, research and extension activities in Agriculture, Horticulture Engineering, product Processing and Home Science. At present there seven Colleges, seventeen Research Centers and six Extension Education Institute working in nine districts of Gujarat namely Ahmedabad, Anand, Dahod, Kheda, Panchmahal, Vadodara, Mahisagar, Botad and Chhotaudepur AAU's activities have expanded to span newer commodity sectors such as soil health card, bio-diesel, medicinal plants apart from the mandatory ones like rice, maize, tobacco, vegetable crops, fruit crops, forage crops, animal breeding, nutrition and dairy products etc. the core of AAU's operating philosophy however, continues to create the partnership between the rural people and committed academic as the basic for sustainable rural development. In pursuing its various programmes AAU's overall mission is to promote sustainable growth and economic independence in rural society. AAU aims to do this through education, research and extension education. Thus, AAU works towards the empowerment of the farmers.

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2018 - 20202
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Subject: Veterinary Pharmacology and Toxicology × Start date: 2014 × Type: Thesis × Thesis Type: Ph.D ×
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    ThesisItemOpen Access
    STUDIES ON EFFECT OF FLUNIXIN MEGLUMINE AND FEBRILE CONDITION ON PHARMACOKINETICS OF CEFPIROME AND SAFETY OF SIMULTANEOUS ADMINISTRATION OF CEFPIROME AND FLUNIXIN MEGLUMINE IN SHEEP
    (2020) Vaidehi N. Sarvaiya; Dr. A. M. Thaker
    Cefpirome is a novel fourth generation cephalosporin with bactericidal action. Synergistic interaction between NSAID and antibiotic can potentially prevent the emergence of resistance, increase antibacterial efficacy and provide broader-spectrum of antibacterial activity than antibiotic monotherapy. Flunixin meglumine (FM) is used as adjunctive therapy in the treatment of sepsis and various inflammatory conditions in different ruminant species. Along with this fact, fever is also one of the most common manifestations in bacterial diseases. Looking to these overall points, the study was conducted to evaluate the effect of intramuscularly administered FM (1.1 mg/kg) and lipopolysaccharide (LPS) induced febrile condition on pharmacokinetics of cefpirome following intravenous (IV) and intramuscular (IM) administrations (10 mg/kg) in sheep and safety of simultaneous administrations of cefpirome (10 mg/kg, IM) with FM (1.1 mg/kg, IM) for five days in sheep by monitoring hematological and blood biochemical profiles, as these kinds of literature is not available in sheep. Cefpirome was assayed in plasma by HPLC.
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    ThesisItemOpen Access
    STUDIES ON PHARMACOKINETICS AND SAFETY OF GEMIFLOXACIN ALONE AND WITH PIPERINE IN LAYER BIRDS
    (COLLEGE OF VETERINARY SCIENCE AND ANIMAL HUSBANDRY ANAND AGRICULTURAL UNIVERSITY ANAND, 2018) MARADIYA JAYESH JASAMAT; Dr. A. M. Thaker
    Gemifloxacin, a fourth-generation synthetic broad spectrum fluoroquinolone has bactericidal action against broad range of bacteria including those that are resistant to conventional antimicrobial drugs. Piperine, the major plant alkaloid present in pepper, is reported to have bioavailability-enhancing activity for nutritional substances and drugs. Despite the great potential for clinical use of gemifloxacin and beneficial (bioenhancing) effect of piperine on pharmacokinetics of various antimicrobials, the data on pharmacokinetics and safety profile of gemifloxacin and piperine alone as well as with each other in layer birds are not available. Looking to these overall points, the present study was conducted in layer birds to investigate pharmacokinetics of gemifloxacin and piperine alone and in combination with each other at 10 mg/kg dose rate following intravenous and oral administration as well as safety of both drugs alone and together at same dose rate by daily oral administration for 5 days. Liquid chromatography with mass spectrometry (LC-MS/MS) method was developed and validated for the simultaneous estimation of gemifloxacin and piperine concentration in plasma samples of the present pharmacokinetics study in layer birds.