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  • ThesisItemOpen Access
    ROMIFIDINE SEDATION WITH KETAMINE OR PROPOFOL INDUCTION FOR ISOFLURANE ANAESTHESIA IN GOATS
    (KARNATAKA VETERINARY ANIMAL AND FISHERIES SCIENCE'SUNIVERSITY, BIDAR-585226, 2018-07) CHAMANVALI, B.; D. DILIPKUMAR; S. M. USTURGE; B.V. SHIVAPRAKASH
    The study was carried out to evaluate the feasibility of romifidine sedation for ketamine or propofol-isoflurane general anaesthesia for various surgeries in goats. The study was carried out in 12 clinical cases of goats presented for various surgical procedures and were randomly divided into two groups consisting of six goats in each group. The goats of both the groups were premedicated with romifidine hydrochloride (50µg/kg, IV). After ten minutes the animals of group I and II were induced with ketamine (6 mg/kg, IV) and propofol (6mg/kg IV) respectively then anaesthesia maintained with isoflurane (1-2%) in both the groups. Onset of sedation, down time to sternal recumbency were faster in both the groups. Ketamine-isoflurane was associated with better haemodynamic stability in comparison to propofol-isoflurane. However, propofol induction had advantage of excellent sedation and muscle relaxation. Haemoglobin and total erythrocyte count decreased non-significantly, whereas, packed cell volume and total leukocyte count decreased significantly at maximum depth of anaesthesia in both the groups. All the haemato-biochemical changes were within physiological limits. The preanesthetic and the general anaesthetic combinations followed in both the groups provided satisfactory surgical plane of anaesthesia and were ideal and safe to perform major surgeries in goats without any complications.