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  • ThesisItemOpen Access
    PATHOLOGY OF PNEUMOENTERIC INFECTIONS OF POULTRY IN AND AROUND BIDAR
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR-585401, 2005-09-01) MANJUNATHA S. S.; D.T.NAIK
    The present investigation was taken up to study the prevalence of pneumoenteric infections of poultry in and around Bidar. The study was designed to find out the probable disease conditions causing pneumoenteric lesions, based on gross and histopathological findings. During the present study, a total of 500 samples comprising of trachea, lungs and intestines were examined for the presence of either pneumonic or enteric lesions. A systematic screening of these samples revealed various pathological changes on gross and histopathological examinations. The results indicated 45.8 per cent pneumonic infections and 33.8 per cent enteric infections in the present study. The proportional disease specific prevalence of various pneumonic conditions of poultry in the present study revealed higher prevalence rate of pneumonia due to bacterial agents (46.29%), followed by miscellaneous agents (27.95%) and viral agents (25.76%). The proportional disease specific prevalence of various enteric infections of poultry in the present study indicated higher prevalence of parasitic enteritis (48.52%) when compared to bacterial (35.5%) and viral enteritis (15.98%).
  • ThesisItemOpen Access
    EFFICACY OF ZINC OXIDE (ZnO) NANOPARTICLES IN DIETHYLNITROSAMINE (DEN) INDUCED HEPATOCARCINOGENESIS IN RATS
    (KARNATAKA VETERINARY, ANIMAL & FISHERIES SCIENCES UNIVERSITY, BIDAR, 2018-07) JEEVAN, K; Dr. SUGUNA RAO
    The present study was carried out to determine the prophylactic and therapeutic anticancerous efficacy of Zinc oxide nanoparticles (ZnO NPs) against DEN induced hepatocarcinogenesis in rats. The various groups in the study included negative control (Group I), DEN control (Group II), ZnO NPs control (Group III), ZnO NPs and DEN concurrent group (Group IV), ZnO NPs pre-treatment group (Group V) and ZnO NPs post-treatment group (Group VI). Hepatocarcinogenesis was induced by single intraperitoneal injection of DEN (100 mg/kg) on Day one followed by 0.01 % DEN in drinking water ad libitum throughout the study period. Induction of hepatocarcinogenesis was determined by the appearance of grayish white nodules on the surface of liver grossly and confirmed by microscopical examination. ZnO NPs were used at a dose rate of 25 mg/kg body weight. The effect of DEN administration and ZnO NPs treatment in different groups were assessed by hemato-biochemical parameters, oxidant and antioxidant prolife, histopathology, immunohistochemical and molecular evaluation of p53 and glutamine synthetase expression. DEN induced hepatocarcinogenesis as early as by 60th day and induced larger growths of hepatocellular carcinoma by 90th day. ZnO NPs concurrent and pre-treatment delayed the onset of DEN induced hepatocarcinogenesis and reduced the number of hepatocellular carcinoma nodules. ZnO NPs post-treatment did not reveal any effect on completely developed hepatic tumors. Based on the results, it was concluded that ZnO NPs have prophylactic effect but no therapeutic effect against DEN induced hepatocarcinogenesis.
  • ThesisItemOpen Access
    STUDIES ON OCCURRENCE OF HEPATIC AND PANCREATIC DISORDERS IN DOGS
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2017-12) HARSHITHA, C.R; Dr. M.L. SATYANARAYANA)
    The present investigation was undertaken to study the occurrence of various pathological conditions in the liver and pancreas of dogs that were presented to the Department of Veterinary Pathology, Veterinary College, Bengaluru. Hepatic lesions were found to be highest in dogs of less than one year, of male sex and non-descript breeds. The lesions were histopathologically classified as vascular changes which include congestion (75.71%), haemorrhage (68.57%) and haematoma (1.42%). Degenerative and necrotic changes which included cell swelling (4.28%), hydropic degeneration (17.14%), fatty change (18.57%) and necrosis (20%). Inflammatory changes included hepatitis (17.14%) and cirrhosis (35.71%). Proliferative changes were hyperplasia of hepatocytes (12.85%) and biliary epithelium (27.14%) and neoplasia (2.85%). Miscellaneous conditions were hemosiderin (28.57%), calcium (2.85%) and bile pigment (20%) deposition. Pancreatic lesions were found to be highest among dogs of above 12 years (22.72%), of male sex (54.54%) and non-descript breeds (36.36%). Microscopically, exocrine pancreatic lesions were classified as vascular changes like congestion (56.81%), haemorrhage (25%) and oedema (4.54%). Degenerative and necrotic changes included degeneration of acinar cells (47.72%), parenchymal necrosis (45.45%), pancreatic fat necrosis (4.54%) and acinar calcification (6.81%). Inflammatory changes recorded were acute (6.81%) and chronic pancreatitis (31.81%). Proliferative changes included hyperplasia of acinar cells (6.81%) and neoplasia (15.90%). Endocrine pancreatic lesions were classified as congestion (11.36%), hypocellularity (18.18%), hypercellularity (11.36%), vacuolar degeneration (25%) and neoplasia (2.27%). Thus, this study concluded that large number of cases revealed abnormality upon microscopic than gross examination, suggesting the need for histopathological evaluation to arrive at accurate diagnosis.
  • ThesisItemOpen Access
    PATHOLOGY OF PNEUMOENTERIC INFECTIONS OF POULTRY IN AND AROUND BIDAR
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2005-09) MANJUNATHA S. S.; D.T.NAIK; D.GOPALAKRISHNA RAO; P.M.THIMMA REDDY; ASHOK PAWAR)
    Poultry farming has emerged as an important sector of agriculture in India. This has been clearly demonstrated by numbers and facts that during the last three decades egg production has doubled and poultry meat production has tripled. This expansion in poultry production is in part due to easy industrialization e.g. short turnover, low establishment cost and efficient disease prophylaxis, when compared with production of other livestock. Among agro-based vocations, poultry farming occupies an important position due to its enormous potentiality to bring about rapid economic growth, particularly benefiting the weaker sections of the society. With the advert of this century, the backyard poultry farming has been transformed into a strong agro-based farming activity. The estimated annual poultry egg and meat production in India has steadily gone up to 44 billion eggs ( 2.2. million tonnes by weight ) from 185 million layers and 1.6 million tonnes of broiler meat by weight from 1.6 billion broilers in 2003 emerging the country as the fourth and fifth large producers of egg and poultry meat respectively in the world, contributing to nearly 4% and 2% of the global output. (Rajvir Singh, 2005).
  • ThesisItemOpen Access
    PATHOLOGY OF GOUT IN BROILER CHICKS
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR 585 401., 2005-09) PRATHAP KUMAR, S.M.; M.L. SATYANARAYANA); S. YATHIRAJ; PLACID E. D’SOUZA; SUGUNA RAO
    The poultry farming activity in India has achieved phenomenal growth in the last few decades. This is well substantiated by the fact that egg and poultry meat production has raised from 5300 millions and 1,21,000 tonnes in 1970 to 34,034 millions and 42,00,000 tonnes respectively in 2002. Inspite of rapid expansion in poultry industry there has been a big gap between the production and demand for poultry products. This has encouraged many farmers to take up poultry farming activity in a big way. Continuous genetic selection for feed efficiency and weight gain in broilers has resulted in gross imbalance of certain organ/system to body mass. Cardiovascular, urinary and digestive systems are overburdened with drastic reduction in reserve function. Function failure of these organ/systems has resulted in emergence of several diseases and disorders, one such disorder currently attracting the attention of researchers and farmers is gout in broilers.
  • ThesisItemOpen Access
    PATHOLOGY OF AFLATOXIN Bi IN CHICK EMBRYOS
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR 585 401., 2005-11) PRADEEP KUMAR RAY; H.D. NARAYANASWAMY; B. UMAKANTHA); L. RANGANATH; L. MUNIAPPA
    Poultry industry has made tremendous progress in the country after independence. Indian Poultry Industry has grown rapidly at a rate of 15% to 20% during the last two decades and is now a Rs. 65 billion mega-industry providing employment to 1.5 million people. The future is even brighter with a growing domestic market, rapid industrialization and economic liberalization. Several breakthroughs in poultry science and technology have led to development of genetically superior birds capable of high production, even under adverse hot climate. The contribution of poultry as animal protein provider has been immense. In 2003 the egg production in India was 4,38,000 million or 3.9 per cent of total world production and meat production was 1.92 million tons or 3.0 per cent of world production. The contribution of poultry industry to gross national product is projected to touch Rs 60,000 crores by 2010 A.D.