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Theses & Dissertations

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1991 - 199912010 - 201812
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Author: Vairamuthu, S ×

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Now showing 1 - 9 of 13
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    PATHOLOGICAL AND MOLECULAR STUDIES IN CANINE CUTANEOUS NEOPLASMS
    (2018) Subapriya, S; Vairamuthu, S; Pazhanivel, N; George, Ravi Sundar; Vijayarani, K; TANUVAS
    The present study was undertaken with the objective to study the cytological, gross, and histopathologic changes in canine cutaneous neoplasms, to evaluate the expression of potential tumour biomarkers as diagnostic and prognostic indicators in different cutaneous neoplasms and to carry out molecular studies in canine cutaneous neoplasms. A total of 160 skin tumours were encountered, 80 cases of epithelial tumours, 35 cases of mesenchymal tumours, 44 round cell tumours and a single case of melanoma. The tumours were recorded in 16 breeds. More males (n=109) were recorded with skin tumours than females (n=51). Location wise, limb 53(33.13%) had the highest occurrence of tumours. Maximum cases of skin tumours 82(50.63%) were recorded in the age group of 6-10 years.
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    CLINICOPATHOLOGICAL EVALUATION OF INFLAMMATORY BOWEL DISEASE AND ITS MANAGEMENT IN DOGS
    (2018) Sandhya Bhavani, M; Kavitha, S; Gowri, B; Vairamuthu, S; Vijayarani, K; TANUVAS
    The study entitled “Clinicopathological evaluation of inflammatory bowel disease and its management in dogs” was carried out to study the clinicopathological changes of inflammatory bowel disease (IBD)in dogs, to assess the usefulness of endoscopy in the diagnosis of IBD and evaluating the therapeutic protocols in the management of IBD. Present study consisted of ten apparently healthy dogs and thirty three clinical cases. The parameters included in this study were clinical examination, haematology, serum biochemistry, faecal examination, radiography, ultrasonography, endoscopy, histopathology, PCR, flowcytometry and special diagnostic tests (serum CRP, cobalamin and folate).
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    DEVELOPMENT OF MOLECULAR BASED DIAGNOSTIC KIT FOR DETECTION OF ANTIBIOTIC RESIDUES IN MEAT AND MILK
    (2018) Ruth Sophila, J; Kumanan, K; Sarath Chandra, G; Vairamuthu, S; TANUVAS
    Food safety is an essential requirement for consumers. One of the key challenges to ensure food safety is the availability of rapid, sensitive, cost-effective pen-side tests to identify specific hazards such as presence of antibiotic residues. This need was fulfilled in this study by the development of a microbial inhibition assay (MIA) using the vegetative form of Geobacillus stearothermophilus as indicator organism to screen for the presence of antibiotic residues in chicken meat and milk. The spectrum of sensitivity to antibiotics was wide with Geobacillus stearothermophilus and B. subtilis while E. coli was resistant to 3/16 antibiotics screened. The limit of detection (LOD) in the MIA was 1 ppb for enrofloxacin and 0.5 ppb for ciprofloxacin and oxytetracycline (OTC) in meat matrix. The LOD was 50 ppb for enrofloxacin, 25 ppb for ciprofloxacin, 100 ppb for OTC and 25 ppb for neomycin in milk matrix. Results of screening 56 meat and 55 milk samples collected from in and around Chennai for the presence of antibiotic residues using the developed MIA were negative.
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    CLINICOPATHOLOGICAL, ULTRASONOGRAPHIC EVALUATION AND THERAPEUTIC MANAGEMENT OF SUBACUTE RUMINAL ACIDOSIS (SARA) IN DAIRY CATTLE
    (2018) Mohammed Ismail, AL; Kavitha, S; Nagarajan, B; Vairamuthu, S; TANUVAS
    Subacute ruminal acidosis (SARA) is defined as periods of moderately depressed ruminal pH, is one of the most common chronic digestive disorders, especially in well-managed dairy herds. The study was conducted at Large Animal Medicine-Out patient Unit of Madras Veterinary College Teaching Hospital to document clinical, haemato-biochemical, rumen fluid, milk and ultrasonographic changes and to assess the efficacy of treatment protocols in the management of SARA in dairy cattle. In the study, dairy cows with the history of reduced dry matter intake, drop in milk yield and diarrhoea were subjected to detailed physical examination, haemato-biochemical, rumen fluid analysis, serum haptoglobin estimation and ultrasonographic evaluation. Twenty two cows were found to have SARA based on rumen liquor pH ranging from 5.4-6.0. Twenty cows were selected and randomly subjected for treatment trial with oral Sodium bicarbonate at the dose rate of 250gms/ cow/ day and Saccharomyces cerevisiae at the dose rate of 25×109 CFU/ cow/ day for seven consecutive days.
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    CLINICO PATHOLOGICAL CHANGES OF ACUTE PANCREATITIS IN DOGS
    (2018) Mahadimane, Abhilaasha C; Chandrasekaran, D; Kavitha, S; Vairamuthu, S; TANUVAS
    The aim of the present study was to document the clinico pathological changes of acute pancreatitis in dogs and to compare various diagnostic modalities in the early diagnosis of acute pancreatitis in dogs. Suspected dogs with gastrointestinal disorders presented with clinical signs such as acute onset of vomiting, diarrhea and abdominal pain were screened for acute pancreatitis by hematology, serum biochemistry, coagulation profile, pancreatic enzymes and radiography. Forty suspected cases were referred for detailed ultrasonographic evaluation. Fourteen cases with typical ultrasonographic changes were subjected for SNAP cPL estimation. The present study was divided into two groups - Group I consisting of normal healthy dogs (Control) and Group II consisting of dogs with acute pancreatitis.
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    ThesisItemOpen Access
    ENDOCRINE AND BIOCHEMICAL CHANGES IN PYOMETRA IN BITCHES
    (2018) Gogoi, Jayashree; Leela, V; Suganya, G; Shafiuzama, Mohamed; Vairamuthu, S; TANUVAS
    Canine pyometra has been studied extensively in the past few decades to findthe causes and prognostic markers associated with this infective disease of intact bitches, whichis known to cause a systemic inflammatory responses leading to multiple systemicdysfunctions. Besides the well described clinical symptoms andsystemic effects of this disease, limited research on acute phase proteins, antioxidativestatus and lipid peroxidation profile of this condition was done, although hormonal effects have been repeatedly investigated to determine the exact pathophysiology of the disease. In the present study,the changes in hormonal assay, acute phase proteins, antioxidative status and lipid peroxidation of the pyometra affected bitches both pre-operatively and post-operatively till 14days of ovariohysterectomy was studied.
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    ThesisItemOpen Access
    PATHOLOGY, PATHOGENESIS, MOLECULAR DIAGNOSIS AND ASSESSMENT OF PROTECTIVE IMMUNITY OF VIBRO ALGINOLYTICUS VACCINE IN COBIA (RADIYCEUTRON CANASUM)
    (TANUVAS, 2016) Ramesh Kumar, P; Balachandran, C; TANUVAS; Vairamuthu, S; Dhinakar Raj, G; John Kirubaharan, J
    The objectives of the study are (i) to rccord the natural occurrence of vibriosis in cobia, (ii) to investigate the pathological and histomorphological features in experimental Vibrio alginolyricus infection in cobia (Rachycentron canadum) and (iii) to evaluate the protective effect of vaccine against Valginolyticus infection.
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    ThesisItemOpen Access
    A COMPARATIVE STUDY OF CONENTIONAL SUTURE AND STAPLER ANASTOMOSIS FOR GASTRO-INTESTINAL SURGERY IN DOGS
    (TANUVAS, 2016) Ramya, R; Jayaprakash, R; TANUVAS; Ravi Sundar George; Vairamuthu, S
    The study was carried out on 12 clinical cases of dogs that were brought to Madras Veterinary College Teaching Hospital, with a history of gastro-intestinal affections requiring surgical intervention. The cases were selected based upon inclusive and exclusive criteria respectively. Twelve dogs selected for the study were randomly divided into two groups of 6 each. Conventional suture method in group l animals and anastomotic stapler in group II animals with gastro-intestinal obstructions were performed.
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    ThesisItemOpen Access
    RADIOGRAPHIC ASSESSMENT OF LUMBOSACRAL SPINE & COX OF EMORAL JOINT IN GERMAN SHEPHERD DOGS SHOWING HIND LIMB GAIT ABNORMALITY
    (TANUVAS, 2016) Manoj Prabhakar, P; Jayaprakash, R; TANUVAS; Arun Prasad, A; Vairamuthu, S
    The present study was carried out on the clinical cases of German shepherd dogs showing hind limb gait abnormality to the Small Animal Orthopedics unit of Madras Veterinary College Teaching Hospital. A total of 18 dogs With hind limb gait abnormality and 12 number of German shepherd dogs with no gait abnormality which was presented for the routine screening were subjected to the study. Detailed clinical, orthopaedic, neurologic examination were performed to differentiate the affection of lumbosacral disease from coxofemoral joint affection