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Subject: Veterinary Pharmacology ×

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    ThesisItemOpen Access
    LACTATION INDUCTION IN UNPRODUCTIVE DAIRY CATTLE
    (KARNATAKA VETERINARY, ANIMAL AND FISHERIES SCIENCES UNIVERSITY, BIDAR, 2019-06-01) NAGARAJA. K.; JAGADEESH S SANGANAL
    The animals for the present study were selected from various villages of Davanagere district of Karnataka state and carried out during the month of February-2018 to March-2019. Totally 40 cattle with the history of repeat breeding for 10-20 months. Divided into Four groups with 10 animals in each (groups I, II, III and IV, n=10) were treated with 0.1 mg/kg estradiol – 1 7β and 0.25 mg/kg progesterone S/C for seven consecutive days. In groups I was administered with dexamethasone (20 mg/day from day 18 to 20), group II reserpine (5 mg/day on day 8, 10, 12, and 14), group III combination of dexamethasone (20 mg/day from day 14 to 17) with reserpine (5 mg/day from day 14 to 17) and group IV combination of dexamethasone (20 mg/day from day 14 to 17) with metoclopramide (0.1mg/kg/day from 14 to 17) IM. The relative efficacy of various protocols employed for group II, III and IV were 100 per cent while in group I was 90 per cent efficacious. In all the induced animals milking was initiated on day 20 and milking was carried out twice a day in the morning and evening with 12 h interval between the milking. The mean total milk yield for 305 days were 753.07±14.09, 813.88±17.73, 1097.60±17.20 and 1156.95±33.39 liters in group I, II, III and IV respectively. The mean milk fat and SNF composition became identical in naturally calved and induced groups on day from 15 to 25. The mean peak serum 17β-estradiol and progesterone concentration was noticed on day 6 and declined sharply from day 7 onwards and became identical in group I, II, III and IV on day 18 in all the treated groups as compared to control group. The percentage of conception obtained was 40% (4/10), 50% (5/10), 60% (6/10) and 60% (6/10) in group I, II, III and IV respectively. Current study suggested that animals treated with combination of dexamethasone with reserpine and dexamethasone with metoclopramide improves success rates.