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  • ThesisItemOpen Access
    STUDIES ON PREEMPTIVE ANALGESIC EFFECTS ON AMPUTATION OF HORN IN CATTLE
    (SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2006-04) PENCHALAIAH, P; SURESH KUMAR, R.V(MAJOR); HARA GOPAL, V; SRILATH, Ch
    ABSTRACT: Twelve cattle undergoing amputation of horn procedures were randomly divided in to two groups. In group I animals surgery was performed following standard procedure and in group I1 meloxicam was administered at the dose rate of 0.2 mg per kilo gram body weight intravenously 30 minutes before anesthesia and surgery. Preemptive analgesic effects were evaluated by physiological, haematological, pulse oxymetric, and biochemical studies. Meloxicam did not alter rectal temperature and pulse rate values in the present study. Though the respiratory rates showed the significant rise in both the groups these were within the normal physiological range. Pulse oxymetric studies revealed no sigruficant changes in Sp02values in both the groups. Total erythrocyte values showed sigmficant reduction in group I whereas the changes were not sigruficant in meloxicam treated group. Both the groups showed leukocytosis, neutrophilia, and lymphocytopenia, more sigruficantly in group I compared to group 11. Haemoglobin and packed cell volume values were sigruficantly reduced in group I compared to group LI. Biochemical parameters like cortisol, C-reactive protein and glucose were sigruficantly increased in group I where as meloxicam treated animals showed non sigruficant fluctuations. In conclusion meloxicam a selective COX-2 Inhibitor could be used satisfactorily as a preemptive analgesic to reduce post operative pain in amputation of horn in cattle.
  • ThesisItemOpen Access
    STUDIES ON FENTANYL PREMEDICATION ON CERTAIN ANAESTHETIC COMBINATIONS IN CANINES
    (SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2006-02) KRISHNA VENI, L; SURESH KUMAR, R.V(MAJOR); SREENU, MAKKENA; SRILATHA, Ch.
    ABSTRACT: The present study was conducted on twelve animals to study the effect of fentanyl premedication on different anaesthetic combinations in bitches which were divided into two groups of six animals in each group. Fentanyl was administered in both the groups @ 2 mdkg body weight intravenously. Later xylazine and thiopentone sodium (2.5%) were given intravenously at the dose rate of 1 mg and 10 mg/kg body weight respectively in group I. In group I1 propofol and thiopentone sodium (2.5%) were administered intravenously at the dose rate of 5 mg and 10 mgkg body weight, respectively. Induction was smooth and excellent without any struggling in both the groups. Good muscle relaxation and early abolishing of all reflexes were noticed in group I1 animals compared to group I. The recovery was smooth and uneventful without any post anaesthetic complications in both the groups, however it was early in group 11.Rectal temperature showed nonsignificant fall upto 60 min in both the groups and were within normal range. Respiratory rates showed a nonsignificant fall following drug administration in both the groups through out the observation period. Pulse rates showed a significant fall in both the groups throughout the observation period, upto 2 hrs in group I and upto 4 hrs in group 11. SPOz values were within normal physiological range during the entire period of observation. The haematological parameters like TEC, TLC and Hb values did not show any significant changes, however they fluctuated within the normal range. The packed cell volume values in group I showed a significant fall upto 2 hrs after drug administration whereas group I1 animals recorded a significant rise at 60 minutes observation period. Changes in ALT, AST, glucose and protein were not statistically significant and fluctuated within the normal physiological range in both the groups.