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ThesisItem Open Access STUDIES ON PREEMPTIVE ANALGESIC EFFECTS ON AMPUTATION OF HORN IN CATTLE(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2006-04) PENCHALAIAH, P; SURESH KUMAR, R.V(MAJOR); HARA GOPAL, V; SRILATH, ChABSTRACT: Twelve cattle undergoing amputation of horn procedures were randomly divided in to two groups. In group I animals surgery was performed following standard procedure and in group I1 meloxicam was administered at the dose rate of 0.2 mg per kilo gram body weight intravenously 30 minutes before anesthesia and surgery. Preemptive analgesic effects were evaluated by physiological, haematological, pulse oxymetric, and biochemical studies. Meloxicam did not alter rectal temperature and pulse rate values in the present study. Though the respiratory rates showed the significant rise in both the groups these were within the normal physiological range. Pulse oxymetric studies revealed no sigruficant changes in Sp02values in both the groups. Total erythrocyte values showed sigmficant reduction in group I whereas the changes were not sigruficant in meloxicam treated group. Both the groups showed leukocytosis, neutrophilia, and lymphocytopenia, more sigruficantly in group I compared to group 11. Haemoglobin and packed cell volume values were sigruficantly reduced in group I compared to group LI. Biochemical parameters like cortisol, C-reactive protein and glucose were sigruficantly increased in group I where as meloxicam treated animals showed non sigruficant fluctuations. In conclusion meloxicam a selective COX-2 Inhibitor could be used satisfactorily as a preemptive analgesic to reduce post operative pain in amputation of horn in cattle.ThesisItem Open Access STUDIES ON FENTANYL PREMEDICATION ON CERTAIN ANAESTHETIC COMBINATIONS IN CANINES(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2006-02) KRISHNA VENI, L; SURESH KUMAR, R.V(MAJOR); SREENU, MAKKENA; SRILATHA, Ch.ABSTRACT: The present study was conducted on twelve animals to study the effect of fentanyl premedication on different anaesthetic combinations in bitches which were divided into two groups of six animals in each group. Fentanyl was administered in both the groups @ 2 mdkg body weight intravenously. Later xylazine and thiopentone sodium (2.5%) were given intravenously at the dose rate of 1 mg and 10 mg/kg body weight respectively in group I. In group I1 propofol and thiopentone sodium (2.5%) were administered intravenously at the dose rate of 5 mg and 10 mgkg body weight, respectively. Induction was smooth and excellent without any struggling in both the groups. Good muscle relaxation and early abolishing of all reflexes were noticed in group I1 animals compared to group I. The recovery was smooth and uneventful without any post anaesthetic complications in both the groups, however it was early in group 11.Rectal temperature showed nonsignificant fall upto 60 min in both the groups and were within normal range. Respiratory rates showed a nonsignificant fall following drug administration in both the groups through out the observation period. Pulse rates showed a significant fall in both the groups throughout the observation period, upto 2 hrs in group I and upto 4 hrs in group 11. SPOz values were within normal physiological range during the entire period of observation. The haematological parameters like TEC, TLC and Hb values did not show any significant changes, however they fluctuated within the normal range. The packed cell volume values in group I showed a significant fall upto 2 hrs after drug administration whereas group I1 animals recorded a significant rise at 60 minutes observation period. Changes in ALT, AST, glucose and protein were not statistically significant and fluctuated within the normal physiological range in both the groups.ThesisItem Open Access CLINICAL EVALUATION OF ZEPP’S AURAL RESECTION AND VERTICAL EAR CANAL ABLATION IN THE TREATMENT OF CHRONIC OTITIS EXTERNA IN DOGS(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2003-07) JAGAN MOHAN REDDY, K; Chandrasekhar, E.L(Major); Raghavender, K.B.P.; Anjaneyulu, YABSTRACT : The present clinical study was carried out on 88 dogs presented for treatment of chronic otitis externa. In 74 dogs (84.09%) medical treatment was performed and in the remaining 14 dogs surgical treatment was undertaken. Out of these 14 dogs, 7 dogs were treated by performing Zepp‟s aural resection and the remaining 7 dogs were treated by performing vertical ear canal ablation. The mean age of presentation of dogs with otitis externa requiring medical treatment was found to be 5.21 ± 0.27 years. For surgical cases the mean age were found to be 7.07 ± 0.23 years. The results revealed that a majority of cases of chronic otitis externa were noticed in German Shepherd followed by Spitz, Mongrels, Labrador, Doberman and Dachshund. The various clinical signs of otitis externa were head shaking, scratching, pain odour, ear discharges and head tilt. Visual examination of ear canal revealed hyperplasia, thickening, ulceration, stenosis and calcification of ear canals in 14 cases. These cases were selected for surgical treatment. Out of 88 dogs examined 27 dogs had unilateral ear disease and 61 dogs had bilateral ear disease. The results of cultural examination of the ear discharges resulted in isolation of Staphylococcus sp., in 51 cases, Pseudomonas in 24 cases and E. coli in 13 cases. Ciprofloxacin was found to be the most effective drug with 31 cases responding to the drug, followed by Gentamycin in 25 cases, Chloramphenicol in 22 cases, Amoxycillin in 6 cases and Oxytetracycline in 4 cases. Medical treatment comprised of through irrigation of the external ear canal followed by topical and parenteral antibiotics as determined by antibiotic sensitivity test. Medical treatment of 74 dogs resulted in alleviation of symptoms in 62 (83.78%) dogs while six dogs had relapse of symptoms after 4-6 weeks. Treatment of these six dogs with the same treatment regimen led to recovery. Six dogs were not available for follow up. All the seven dogs where Zepp‟s aural resection was performed recovered uneventfully. Wound dehiscence was observed in one case. All the dogs recovered without any post-operative complications. All the seven dogs that had advanced chronic otitis externa with symptoms like hyperplasia and complete or partial stenosis of the ear canal were relieved from the clinical symptoms of otitis externa by performing vertical ear canal ablation. Barring one case of wound dehiscence, no complications were observed in any of the dogs. Histopathological examination of the resected portions of the ear canal revealed the presence of severe cellular infiltration, congestion, extensive fibroblastic proliferation, and attempts of ossification.ThesisItem Open Access Surgical Affections of External Ear In Dogs- A Clinical Study(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2002-07) Rajendra Kumar, Renukuntla; Raghavender, K.B.P(MAJOR); Chandrasekhar, E.L; Nagamalleswari, YThesisItem Open Access Studies On The Efficacy Of Peritoneal And mesenteric Onlay Grafts For Intestinal Healing In Bovine Calves(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2001-09) Ravindranadh Tagore, V; Sreenu, Makkena(MAJOR); Suresh Kumar, R.V.; Chandra Sekhara Rao, T.SThesisItem Open Access Comparative Studies Of Certain Intramuscular Anaesthetic Drug Combination In Dogs(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2001-09) Visweswar, K.C; Haragopal, V(MAJOR); Madhava Rao, T; Nagamalleswari, YThesisItem Open Access Studies On Propofol-Ketamine Anaesthesia In Dogs(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2000-11) Venugopal, A; Chandrasekhar, E.L(Major); Hara Gopal, V; Nagamalleswari, YThesisItem Open Access Studies On Therapeutic Efficacy Of Synovial Fluid Transfusion In Combination With Steroidal And Non-Steroidal Anti-Inflammatory Drugs In Induced Traumatic Arthritis In Buffalo Calves(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2000-11) Narasimha Reddy, M; Haragopal, V(MAJOR); Madhava Rao, T; Nagamalleswari, YThesisItem Open Access Repair Of Avulsion Fractures Of Anterior Tuberosity Of Tibia In Dogs-A Comparative Study(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2000-01) Raghotham Reddy, Vellanki; Haragopal, V(MAJOR); Raghavender, K.B.P.; Iyyangar, M.P