Browsing by Author "Ranganathan, V."
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OtherItem Open Access Assessment of Cell Mediated Immune Response in Rabbits Fed with Cassia Occidentalis(2012) Ranganathan, V.; Selvasubramanian, S.; TANUVASArticleItem Unknown Concentrations of Lead and Endosulfan on Certain Biochemical Parameters in Wistar Rats(2016-06) Ranganathan, V.; Malik, Jitendra Kumar; Babu, Naraharisetti Suresh; Aggarwal, Manoj; Rao, G.S.; Sankar, P.; TANUVASThe effect of concurrent repeated exposure of higher concentrations of lead and endosulfan were evaluated on certain biochemical parameters in male wistar rats. Rats of group I served as untreated control where as Group II received drinking water containing lead as lead acetate @1000 ppm (Pb1000). Group III was exposed to feed containing technical grade endosulfan @ 10 ppm (E100). Group IV was exposed to Pb (1000) +E (100). Blood and target organs were collected for estimation of biochemical parameters to assess toxicity by combination of these two chemicals at higher doses. The results suggest that higher doses of endoulfan and lead alone and in combination may modify general biochemical parameters carried out in the study.OtherItem Open Access Control of Early Chick Mortality in Japanese Quail (Coturnix Coturnix Japonica) Using Ethno Veterinary Medicine - A Case Report(TANUVAS, 2010) Punniamurthy, N.; Babu, M.; Ranganathan, V.; Manohar, B. MuraliOtherItem Open Access Disease Pattern of Sheep and Goats in an Organised Farm(TANUVAS, Chennai, 2011-12) Sundaravinayaki, M.; Ranganathan, V.; Thangadurai, R.; Chellapandian, M.ArticleItem Open Access Effect Of Concurrent Exposure Of Lower Concentrations Of Lead And Endosulfan On General Biochemical Parameters In Wistar Rats(2016-06) Ranganathan, V.; Malik, Jitendra Kumar; Babu, Naraharisetti Suresh; Aggarwal, Manoj; Rao, G.S.; Sankar, P.; TANUVASThe effect of concurrent repeated exposure of lower concentrations of lead and endosulfan were evaluated on general biochemical parameters in male wistar rats. Rats of group I served as untreated control where as Group II received drinking water containing lead as lead acetate @100 ppm (Pb100). Group III was exposed to feed containing technical grade endosulfan @ 10 ppm (E10). Group IV was exposed to Pb (100) +E (10). Blood and target organs were collected for estimation of general biochemical parameters to assess toxicity by combination of these two chemicals at lower doses. The results suggest that the lower doses of endoulfan and lead alone and in combination did not change general biochemical parameters carried out in the study.ArticleItem Open Access Effect of Concurrent Exposure of Lower Concentrations of Lead and Endosulfan on Hepatic Drug Metabolizing Enzymes in Male Rats(2016-04) Ranganathan, V.; Malik, Jitendra Kumar; Babu, Naraharisetti Suresh; Aggarwa, Manoj; Rao, G.S.; Sankar, P.; TANUVASThe effect of concurrent repeated exposure of lower concentrations of lead and endosulfan were evaluated on hepatic drug metabolizing enzymes in male rats. Alterations were evaluated through changes in the phase I enzymes (viz. cytochrome P450 and cytochrome b5, aminopyrine N – demethylase and aniline p- hydroxylase) activity and phase II enzymes (viz. microsomal and cytosolic glutathione-S-transferase UDP-glucuronosyl transferase) activity in liver. Lead, when given alone at the dose of 100 ppm in drinking water and endosufan, when given alone at the dose of 10 ppm in feed, and given in combination did not change the activities of cytochrome b5, aminopyrine N – demethylase and aniline phydroxylase. When given in lower dose combination, they significantly inhibited levels of cytochrome 450, microsomal, cytosolic glutathione-S transferase and microsomal protein as compared to control and their single compounds when given alone. This study suggested that activities of xenobiotic drug metabolizing enzymes by repeated exposure to lead and endosulfan at the concentrations used in the study were not modified to produce significant toxicity in case of combined exposure.ArticleItem Open Access Effect of Fenbendazole on Growth Promotion in Mecheri Lambs(Veterinary World, 2013-02) Ranganathan, V.; Vasanthakumar, S.; Muralidharan, J.; Karunanithi, K.; TANUVASAim: The objective of the study was to find out the effect of fenbendazole on the growth promotion in stunted mecheri lambs. Materials and methods: The study was conducted with three groups of ten mecheri lambs each. Group I served as untreated control and group II and III were treated with fenbendazole @ 5 mg/kg body weight and 7.5 mg/kg body weight, respectively. All the lambs were subjected to haemato-biochemical observations, body weight recording and collection of faeces for egg counting before and after the treatment. Results: Fenbendazole in both the doses had beneficial effect on haemato-biochemical observations like haemoglobin, total erythrocyte count, total protein, albumin, aspartate aminotransferase and alanine aminotransferase besides showing efficacy as an anthelmintic. The drug also increased body weight gain significantly at higher dose as compared to untreated control. Conclusion: The results support that fenbendazole has the potential for modulating growth of stunted mecheri lambs.OtherItem Open Access Effect of Herbal Preparation on the Management of Clinical Mastitis in Jersey Cross Cows(TANUVAS, Chennai, 2013-06) Punniamurthy, N.; Ranganathan, V.; Kumar, S. Sathesh; Kumar, M. SathishArticleItem Open Access EFFECT OF SIMULTANEOUS EXPOSURE OF LEAD AND ENDOSULFAN AT HIGHER CONCENTRATIONS ON HUMORAL IMMUNITY IN RATS(Indian Veterinary Association Kerala, 2015-11) Ranganathan, V.; Malik, J.K.; Rao, G.S.; TANUVASFive groups of six rats were taken for the study. Rats of group I served as untreated control where as Group II received drinking Water containing lead as lead acetate @1000 ppm (Pb1000). Group III was exposed to feed containing technical grade endosulfan @ 100 ppm (E100) and Group IV Was exposed to Pb (1000) +E (100), respectively. Group V Was treated as stimulated control group. All the treatments were given daily for 28 days. On 0, 7, 14, 21 and 28th day serum samples were col- lected from all groups of animals. Indirect ELISA was performed along with biochemical parameters. The results suggest that the higher concentrations of endosulfan and lead alone and in combination produced significant alterations in the humoral immune response in rats.OtherItem Open Access Effect of Simultaneous Exposure Of Lead And Endosulfan at Higher Concentrations On I-Iumoral Immunity In Rats(TANUVAS, Chennai, 2014-12) Ranganathan, V.; Malik, J.K.; Rao, G.S.; Aggarwal, M.Endosulfan is a member of the cyclodiene group of organochlorine pesticides used around the world for applications on vegetables, fruits, and non-food crops such as cotton and tobacco. Lead has been known as a toxic metal since ancient times, and has been studied for its toxic effects since the middle ages. Toxiological consequences due to simultaneous exposure of these compounds have not been studied.OtherItem Open Access Effects Of Novel Water Soluble Nanocurcumin On Arsenic-Induced Genotoxicity In Rats(TANUVAS, Chennai, 2014-12) Sankar, P.; Senthilkumar, P.; Ranganathan, V.Poly (lactic-coglycolic acid) encapsulated curcumin nanoparticles (CUR-NP) were synthesized to explore their therapeutic application of arsenic-induced genotoxicity in rats. The CUR-NP prepared by emulsion technique was spherical in shape with an encapsulation efficiency of 86.5%.ArticleItem Open Access Estimation of humoral immune response in rabbits fed with Cucurbita maxima seeds(Veterinary World, 2013-07) Ranganathan, V.; Selvasubramanian, S.; Vasanthakumar, S.; TANUVASAim : The objective of the study was to estimate the humoral immune response in rabbits treated with Cucurbita maxima seeds. Materials and Methods: Thirty six male Newzealand White rabbits were divided into six groups (I, II, III, IV, V, VI) of six in each. Group I was the untreated control. Group II was treated with dexamethasone sodium (2 mg/Kg, i.m) for 7 days. Group III was treated with levamisole hydrochloride at 2.5 mg/kg (s.c) thrice a week. Group IV was treated with Cucurbita maxima seeds. Group V was treated with levamisole and dexamethasone and Group VI was treated with dexamethasone and Cucurbita maxima seeds. The seed was given @ 1000 mg/kg orally for 10 days. Antibody titre and serum immunoglobulin concentration were estimated along with haematology. Results: Dexamethasone caused significant decreases in the antibody titre, immunoglobulin concentration where as Curcurbita maxima, Dexamethasone + Curcurbita maxima and dexamethasone + levamisole groups showed significant increase in these entities. There were no significant differences in RBC count, Haemoglobin contents among all the groups studied. Conclusion: Results suggest that Cucurbita maxima seeds has the ability to stimulate humoral immune response in rabbits.ArticleItem Open Access Ethno Veterinary Practices for Combating Antimicrobial Resistance(2017-02) Ranganathan, V.; TANUVASPrevalence of drug resistance has been reported in many pathogens over the years in different regions of the world including developing countries. Resistance can be described as intrinsic and acquired resistance. Issues related to antimicrobial resistance may be avoided by facilitating herbal research in academia with hypotheses rested with traditional healers of animals. Ethno veterinary medicines can be advocated successfully for the primary health care of livestock and poultry against several microbial diseases. This practice also minimizes the possibility of residues in milk, meat and egg.OtherItem Open Access EVALUATlON OF HEPATOPROTECTIVE ACTIVITY OF Irldigofera aspalathoides IN CHICKEN BY REAL TIME PCR(2014-12) Ranganathan, V.; Punniamurthy, N.; Ahamad, D. Basheer; Satheshkumar, S.; TANUVASThe present study was conducted lo evaluate the hepatoprotective activity of medicinal plant, Indigofera aspalathoides on paracetamol induced hepatotoxicity in White Leghorn cockerels. Birds were divided into five groups of 6 birds each and group I served aswuntrea ted control and was given distilled water for 23 days continuously.OtherItem Open Access EVALUATlON OF HEPATOPROTECTIVE ACTIVITY OF Irldigofera aspalathoides IN CHICKEN BY REAL TIME PCR(2014-12) Ranganathan, V.; Punniamurthy, N.; Ahamad, D. Basheer; Satheshkumar, S.; TANUVASOtherItem Open Access Fluoride Intoxication in Cattle of Eloor Industrial Area, Kerala Due to Industrial Pollution(TANUVAS, Chennai, 2014-12) Senthilkumar, P.; Aravindakshan, C.M.; Ranganathan, V.; Sankar, P.Industrial processes have been directly or indirectly responsible for the release of toxic pollutants in the environment. Of all pollutants, which affect farm animals, fluorine causes more and widespread damage. The study was conducted to assess the extent of fluoride intoxication in the cattle of Eloor industrial area, Ernakulam district, Kerala.OtherItem Open Access Follicular Turnover and Oestrus Induction in Response to Herbal Treatment in Postpartum Anoestrus Cows(TANUVAS, Chennai, 2013-01) Punniamurthy, N.; Satheskumar, S.; Ranganathan, V.; Babu, M.; Ramakrishnan, N.OtherItem Open Access Hepatoprotective Activity of Basella Rubra on Paracetamol Induced Toxicity in Rats(2012) Punniamurthy, N.; Ranganathan, V.; Ahamad, D. Basheer; Satheshkumar, S.; Sathiskumar, M.; KannanThe present study was conducted to evaluate the hepatoprotective activity of medicinal plant Basella rubra, on paracetamol induced hepatotoxicity in male wistar rats. Rats were divided into 5 groups of 6 rats each and rats in group I served as untreated control and were given distilled water for 23 days.