Clinical study on canine cystic endometrial hyperplasia complex
| dc.contributor.advisor | Das, Arup Kumar | |
| dc.contributor.author | Pushpa | |
| dc.date.accessioned | 2018-06-20T11:18:42Z | |
| dc.date.available | 2018-06-20T11:18:42Z | |
| dc.date.issued | 2017-06 | |
| dc.description.abstract | The objectives of the study were to evaluate the effect of CEH-P on clinical, haematobiochemical and hormonal profile of dogs and changes after OH. Cystic endometrial hyperplasia is a pathological complex which incorporates conditions like cystic ovary, endometrial hyperplasia and accumulation of mucoid material in the lumen of the uterus which might be invaded by opportunistic bacteria and may gradually proceed to pyometra. This study was conducted on 18 female dogs and divided in to two groups in group A 12 female dogs with symptoms of endometrial hyperplasia complex were diagnosed and in group B rest of 6 female dogs were operated for elective ovarianhysterectomy and such animals were kept as control group. Clinical parameters, haematobiochemical parameters, hormonal profile and histo-pathological examination were observed for all the 18 animals just before the operative procedure and after 45 days of the ovarian-hysterectomy. The hormonal profile (estradiol, progesterone, LH and FSH) of the animals revealed that significant differences in the levels of steroid hormones mainly in progesterone and estrogen in female dogs suffering from cystic endometrial hyperplasia complex as compared to normal female dogs and most of the animal suffering from CEHP complex were having either history of pervious hormonal treatment or they were not bred several years before showing symptoms so there is disturbances in level of steroidal hormone mostly progesterone, which causes increases sensitivity of animals for development of pyometra and CEH. Levels of these hormones after ovarian hysterectomy procedure reduced significantly (109.67 pg/ml, 4.25 ng/ml 17.76pg/ml to, 0.17ng/ml estrogen and progesterone pre and post operatively respectively). This study concludes that in this pathological condition of the uterus the levels of steroid hormones increases, change in their receptors and exogenous administration of theses hormone may play an important role in pathogenesis of CEH-P complex. The main hormone responsible for CEH-P Complex is Progesterone. FSH and LH are not play important role in development of CEH-P complex. The ovariohisterectomuy is choice of treatment for pyometra in female dogs. | en_US |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810054649 | |
| dc.keywords | clinical aspects, canine, endometrium, cystic degeneration, hyperplasia | en_US |
| dc.language.iso | en | en_US |
| dc.pages | 85 | en_US |
| dc.publisher | G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand) | en_US |
| dc.research.problem | Dogs | en_US |
| dc.sub | Veterinary Surgery and Radiology | en_US |
| dc.subject | null | en_US |
| dc.theme | Veterinary Gynaecology and Obstetrics | en_US |
| dc.these.type | M.V.Sc. | en_US |
| dc.title | Clinical study on canine cystic endometrial hyperplasia complex | en_US |
| dc.type | Thesis | en_US |