Effect of methyl ergometrine with or without ceftiofur and nutritional supplements on uterine involution and post partum fertility in crossbred cows
| dc.contributor.advisor | Sharma, Mridula | |
| dc.contributor.author | Madhwal, Deepa | |
| dc.date.accessioned | 2019-09-12T05:54:48Z | |
| dc.date.available | 2019-09-12T05:54:48Z | |
| dc.date.issued | 2019-08 | |
| dc.description.abstract | The present research work was conducted to observe the effect of methyl ergometrine maleate alone and in combinations with Calcium, Phosphorous, Vitamin. (A, D and E) and ceftiofur on uterine involution and post partum fertility. Normally calved 36 CB cows were selected and divided into 6 groups (T1 to T5 and C) with 6 cows in each groups. Treatment 1- Methyl ergometrine (ME) (Ergovet, @ 10 ml, IM, OD), at 1/2 hour of delivery of calf, then second and third day post partum given in all groups except control. Treatment 2- Along with ME, calcium (Mifex, @ 300 ml, IV) and phosphorous (Tonophosphan, @ 10 ml, IM) OD, on second day post partum. Treatment 3- Vit. A, D and E (Intavita, @ 10 ml, IM, OD) on second day post partum was given along with ME. Treatment 4- ME and Ceftiofur sodium (Xyrofur @ 1gm, IM, OD) from second day for three days. Treatment 5- All combinations were given accordingly. Control group 6- Cows were left untreated. Cows were examined for expulsion of fetal membrane, days required for cessation of lochial discharge, reduction of cervical and uterine diameter by ultrasonography and by per rectal palpation, first post partum detectable estrus and first service conception rate. Blood was collected for estimation of blood glucose concentration and plasma progesterone concentration. The expulsion of fetal membrane was significantly (p ˂ 0.05) earlier then untreated group. Days required for cessation of lochial discharge in T5 was significantly (p ˂ 0.05) lower as compared to control and in T1, T2, T3 and T4 it was also significantly (p ˂ 0.05) lower as compared to control. Significant (p ˂ 0.05) reduction in cervical and uterine diameter was in T5 was observed as compared to control. Previously gravid horn and nongravid horn were reached in pelvic brim earlier in T1, T2, T3, T4 and T5 as compared to control groups and non significant reduction in uterine diameter was observed from day 27 to 32 (T5), day 32 to 37 (T1, T2, T3, and T4) and from day 37 to 40 (control). Uterine involution was significantly (p ˂ 0.05) earlier in T2, T3, T4 and T5 as compared control group. Glucose concentration increased significantly (p ˂ 0.05) in all treatment and control groups from day 0 to day 21 post partum and this increase was significantly (p ˂ 0.05) high in T5 as compared to control group. Progesterone concentration showed no significant difference between groups. It was observed that T5 required the significantly (p ˂ 0.05) less days (34 to 36 days) post partum for first detectable heat as compared to control (40- 46 days) while in T1, T2, T3 and T4, it was varied from 36- 45 days post partum. The FRCR was higher in T5 and T3 as compared to T2 and T4, T1 and Control. Methyl ergometrine is an effective drug to prevent the cases of RFM. And when used along with Calcium, Phosphorous, Vitamins (A, D and E) and Ceftiofur, it improved the uterine involution and post partum fertility. | en_US |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810127451 | |
| dc.keywords | methyl ergometrine, ceftiofur, nutritional state, supplements, uterine, involution, post-partum fertility, crossbreds, cows | en_US |
| dc.language.iso | en | en_US |
| dc.pages | 147 | en_US |
| dc.publisher | G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand) | en_US |
| dc.research.problem | Cows | en_US |
| dc.sub | Veterinary Gynaecology and Obstetrics | en_US |
| dc.subject | null | en_US |
| dc.theme | Crossbreeding | en_US |
| dc.these.type | M.V.Sc. | en_US |
| dc.title | Effect of methyl ergometrine with or without ceftiofur and nutritional supplements on uterine involution and post partum fertility in crossbred cows | en_US |
| dc.type | Thesis | en_US |